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PLAIN-3474 | MED-5363 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| dietary patterns depressive symptoms japanese men women pubmed ncbi abstract objective studies reported associations depressive state specific nutrients foods studies examined association dietary patterns adults investigated association major dietary patterns depressive symptoms japanese methods subjects num municipal employees num men num women aged num years participated health survey time periodic checkup depressive symptoms assessed center epidemiologic studies depression ces-d scale dietary patterns derived principal component analysis consumption num food beverage items assessed validated diet history questionnaire logistic regression analysis estimate odds ratios depressive symptoms ces-d num adjustment potential confounding variables results identified dietary patterns healthy japanese dietary pattern characterized high intakes vegetables fruit mushrooms soy products fewer depressive symptoms multivariate-adjusted odds ratios num confidence intervals depressive symptoms lowest highest tertiles healthy japanese dietary pattern score num reference num num num num num num trend num dietary patterns appreciably depressive symptoms conclusions findings suggest healthy japanese dietary pattern related decreased prevalence depressive status
| 3 |
PLAIN-3474 | MED-5364 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| long chain num fatty acids intake fish consumption suicide cohort japanese men women--the japan public health center-based jphc pubmed ncbi abstract objective eicosapentaenoic acid epa docosahexaenoic acid dha implicated protective suicide uncertain higher intake epa dha fish major source nutrients lowers suicidal risk japanese fish consumption suicide rate high study prospectively examined relation fish epa dha intake suicide japanese men women method subjects num men num women aged num years participated jphc study completed food frequency questionnaire num death december num cox proportional hazards regression model estimate hazard ratio hr num confidence interval ci suicide quintile intake results total num num deaths suicide recorded num num person-years follow-up men women higher intakes fish epa dha lower risk suicide multivariate hrs num ci suicide death highest versus lowest quintile fish consumption num num num num num num men women significantly increased risk suicidal death observed women low intake fish hrs num ci num percentile versus middle quintile num num num conclusions result support protective role higher intake fish epa dha suicide japanese men women copyright num elsevier b v rights reserved
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PLAIN-3474 | MED-5365 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| antioxidants antidepressants fact fiction pubmed ncbi abstract depression medical condition complex biological pattern aetiology involving genetic epigenetic factors environmental stressors recent evidence suggests oxidative stress processes play relevant role pathogenic mechanism s underlying major psychiatric disorders including depression reactive oxygen nitrogen species shown modulate levels activity noradrenaline norepinephrine serotonin dopamine glutamate principal neurotransmitters involved neurobiology depression major depression lowered concentrations endogenous antioxidant compounds vitamin zinc coenzyme num enzymes glutathione peroxidase impairment total antioxidant status observations introduce potential targets development therapeutic interventions based antioxidant compounds present review focuses role oxidative stress processes pathogenesis depression therapeutic potential antioxidant compounds co-adjuvant treatment conventional antidepressants discussed instance n-acetyl-cysteine shown significant benefit depressive symptoms randomized placebo-controlled trial additionally curcumin yellow pigment curry shown strongly interfere neuronal redox homeostasis cns possess antidepressant activity animal models depression ability inhibit monoamine oxidases urgent develop tolerated effective treatments depressive disorders antioxidant treatments promising deserve study
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PLAIN-3474 | MED-5366 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| association mediterranean dietary pattern incidence depression seguimiento universidad de navarra/university navarra fol pubmed ncbi abstract context adherence mediterranean dietary pattern mdp thought reduce inflammatory vascular metabolic processes involved risk clinical depression objective assess association adherence mdp incidence clinical depression design prospective study validated num item food frequency questionnaire assess adherence mdp mdp score positively weighted consumption vegetables fruit nuts cereal legumes fish monounsaturated saturated-fatty-acids ratio moderate alcohol consumption meat meat products whole-fat dairy negatively weighted setting dynamic cohort university graduates seguimiento universidad de navarra/university navarra follow-up sun project participants total num initially healthy spanish participants sun project participated study recruitment began december num ongoing main outcome measure participants classified incident depression free depression antidepressant medication baseline reported physician-made diagnosis clinical depression and/or antidepressant medication follow-up results median follow-up num years num cases depression identified multiple adjusted hazard ratios num confidence intervals depression num upper successive categories adherence mdp taking category lowest adherence reference num num num num num num num num num num num num trend num inverse dose-response relationships found fruit nuts monounsaturated saturated-fatty-acids ratio legumes conclusions results suggest potential protective role mdp regard prevention depressive disorders additional longitudinal studies trials needed confirm findings
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PLAIN-3474 | MED-5367 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| relationship plasma carotenoids depressive symptoms older persons abstract objective examined cross-sectional longitudinal relationship plasma carotenoids depressive symptoms six-year follow-up older persons methods materials research part inchianti study prospective population-based study older persons tuscany italy sample analysis included num women men aged num years older plasma total carotenoids assessed baseline depressive symptoms assessed baseline num num year follow-up center epidemiological studies-depression scale ces-d depressed mood defined ces-d num results baseline higher total carotenoids level lower probability depressed mood num num ci num num num adjustment sociodemographic health inflammation exclusion participants baseline depressed mood antidepressants higher total carotenoids level lower risk incident depressed mood num num ci num num num num year follow-up adjustment confounders baseline ces-d inflammatory marker interleukin num receptor antagonist partially mediated association discussion low plasma concentrations carotenoids depressive symptoms predict development depressive symptoms older persons understanding mechanism association reveal potential targets prevention treatment
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PLAIN-3474 | MED-5368 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| suicide mortality relation dietary intake num num polyunsaturated fatty acids fish equivocal findings num large cohort studies abstract intake num num polyunsaturated fatty acids pufas implicated pathogenesis depression sought estimate association intake fish num num pufas suicide mortality long-term follow-up prospective cohort study biennial questionnaires administered num men enrolled health professionals follow-up study num num num women enrolled nurses health study num num num women enrolled nurses health study ii num num dietary fish num num pufa intakes assessed num years validated food-frequency questionnaire suicide mortality ascertained blind physician review death certificates hospital pathology reports adjusted relative risks suicide mortality estimated multivariable cox proportional hazards models pooled cohorts random-effects meta-analysis pooled multivariable relative risks suicide persons highest quartile intake num num pufas relative lowest quartile ranged num num num pufas ptrend num num num num num pufas ptrend num num find evidence intake num pufas fish lowered risk completed suicide
| 3 |
PLAIN-3474 | MED-5369 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| suicide mortality european union pubmed ncbi abstract background estimated million completed suicides year worldwide response increasing concern suicide europe eurosave european review suicide violence epidemiology study undertaken examine recent trends epidemiology suicide self-inflicted injury mortality european union eu methods suicide self-inflicted injury mortality data num eu countries years num obtained world health organisation european statistical office european commission eurostat national statistical agencies data obtained group deaths classified undetermined violence age-standardized mortality rates calculated examined trends time results finland highest suicide rate greece lowest latest year num age-standardized suicide rates tended lowest mediterranean countries significant downward linear time trends suicide mortality observed countries rates varied markedly countries ireland spain displayed significant upward linear trends suicide mortality portugal highest rate undetermined deaths num num greece lowest num num countries including ireland spain showed significant downward trends deaths due undetermined belgium germany showed borderline significant upward linear trends deaths due undetermined conclusions suicide rates countries decreasing validity data uncertain misclassification contribute geographical temporal variation suicide rates eu countries explain phenomenon detailed research comparing suicide-recording procedures practices eu required absence adequate eu wide data suicide epidemiology effective prevention distressing phenomenon remain elusive
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PLAIN-3474 | MED-5370 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| long chain omega num fatty acids intake fish consumption mental disorders sun cohort study pubmed ncbi abstract background long chain omega num fatty acids num pufa intake fish consumption suggested protective factors neuropsychiatric disorders scarcity large cohort studies assessing association aim study assess association num pufa intake fish consumption mental disorders methods prospective cohort study performed num participants num pufa intake fish consumption ascertained validated semi-quantitative food frequency questionnaire outcomes num years follow-up num incident mental disorder depression anxiety stress num incident depression num incident anxiety logistic regression models generalized additive models fit assess relationship num pufa intake fish consumption incidence outcomes odds ratios num confidence intervals ci calculated results num cases depression num cases anxiety num cases stress observed num year follow-up ors num ci mental disorder successive quintiles energy-adjusted num pufa intake num reference num num num num num num num num num num num num subjects moderate consumption fish fourth quintiles consumption median quintile num num g/day relative risk reduction higher num conclusions potential benefit num pufa intake total mental disorders suggested linear trend apparent
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PLAIN-3474 | MED-5371 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| omega num fatty acids treatment depression systematic review meta-analysis abstract conducted meta-analysis randomized placebo-controlled trials omega num fatty acid treatment major depressive disorder order determine efficacy examine sources heterogeneity trials pubmed num num searched randomized placebo-controlled trials omega num fatty acids major depressive disorder primary outcome measure standardized difference clinical measure depression severity stratified meta-analysis examined effects trial duration trial methodological quality baseline depression severity diagnostic indication dose eicosapentaenoic acid epa docosahexaenoic acid dha omega num preparations omega num fatty acid monotherapy augmentation num randomized placebo-controlled trials examining efficacy omega num fatty acids involving num participants meta-analysis demonstrated significant benefit omega num fatty acid treatment compared placebo smd num num ci num num meta-analysis demonstrated significant heterogeneity publication bias evidence omega num benefit removed adjusting publication bias trim-and-fill method smd num num ci num num secondary analyses suggested trend increased efficacy omega num fatty acids trials lower methodological quality trials shorter duration trials utilized completers intention-to-treat analysis trials study participants greater baseline depression severity current published trials suggest small non-significant benefit omega num fatty acids major depression treatment efficacy observed published literature attributable publication bias | 3 |
PLAIN-3474 | MED-1195 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| antioxidant status association elevated depressive symptoms adults national health nutrition examination surveys num num abstract examined relationship elevated depressive symptoms antioxidant status cross-sectional data national health nutrition examination surveys num num adults aged num num years analyzed depressive symptoms measured patient health questionnaire score cutpoint num define elevated depressive symptoms serum antioxidant status measured serum levels carotenoids retinol free retinyl esters vitamin vitamin main analyses consisted multiple logistic zero-inflated poisson regression models taking account sampling design complexity final sample consisted num adults complete data higher total carotenoid serum level lower likelihood elevated depressive symptoms reduction odds num sd increase exposure num women num dose-response relationship observed serum total carotenoids expressed quartiles num num num mol/l num num num mol/l num num ci num num num p-value trend num significant associations found antioxidant levels carotenoids carotene men women combined lutein+zeaxanthins women control dietary lutein+zeaxanthin intake supplement independent inverse association elevated depressive symptoms adults serum antioxidants significant association depressive symptoms independently total carotenoids covariates conclusion total carotenoids carotene lutein+zeaxanthins serum reduced levels depressive symptoms community-dwelling adults
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PLAIN-3474 | MED-1196 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| dietary pattern depressive symptoms middle age abstract background studies diet depression focused primarily individual nutrients aims examine association dietary patterns depression diet approach method analyses carried data num participants num women age num years whitehall ii prospective cohort dietary patterns identified food heavily loaded vegetables fruits fish processed food heavily loaded sweetened desserts fried food processed meat refined grains high-fat dairy products self-reported depression assessed num years center epidemiologic studies depression ces scale results adjusting potential confounders participants highest tertile food pattern lower odds ces depression num num ci num num lowest tertile contrast high consumption processed food increased odds ces depression num num ci num num conclusions middle-aged participants processed food dietary pattern risk factor ces depression num years food pattern protective
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PLAIN-3474 | MED-1198 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| high-dose ascorbic acid increases intercourse frequency improves mood randomized controlled clinical trial pubmed ncbi abstract background ascorbic acid aa modulates catecholaminergic activity decreases stress reactivity approach anxiety prolactin release improves vascular function increases oxytocin release processes relevant sexual behavior mood methods randomized double-blind placebo-controlled num day trial sustained-release aa num healthy young adults num mg/day cetebe placebo num healthy young adults subjects partners recorded penile-vaginal intercourse fsi noncoital partner sex masturbation daily diaries completed beck depression inventory trial results aa group reported greater fsi hypothesized sexual behavior frequency effect prominent subjects cohabiting sexual partner women aa placebo group experienced decrease beck depression scores conclusions aa appears increase fsi differential benefit noncohabitants suggests central activation disinhibition peripheral mechanism responsible
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PLAIN-3474 | MED-1199 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| tomato-rich diet related depressive symptoms elderly population aged num years population-based cross-sectional analysis pubmed ncbi abstract background enhanced oxidative stress defective anti-oxidant defenses related pathogenesis depressive symptoms lycopene powerful antioxidant carotenoids aim study investigate relationship vegetables including tomatoes/tomato products major source lycopene depressive symptoms community-based elderly population methods analyzed cross-sectional survey including num community-dwelling elderly japanese individuals aged num years older dietary intake assessed valid self-administered diet-history questionnaire depressive symptoms evaluated num item geriatric depression scale num cut-off points num mild severe num severe anti-depressive agents results prevalence mild severe severe depressive symptoms num num adjustments potentially confounding factors odds ratios mild severe depressive symptoms increasing levels tomatoes/tomato products num num num trend num similar relationships observed case severe depressive symptoms contrast relationship observed intake kinds vegetables depressive symptoms limitations cross-sectional study making clinical diagnosis depressive episodes conclusions study demonstrated tomato-rich diet independently related lower prevalence depressive symptoms results suggest tomato-rich diet beneficial effect prevention depressive symptoms studies needed confirm findings copyright num elsevier b v rights reserved
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PLAIN-3474 | MED-1200 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| antioxidants potential therapeutics neuropsychiatric disorders abstract oxidative stress implicated pathophysiology neuropsychiatric disorders schizophrenia bipolar disorder major depression genetic nongenetic factors found increased cellular levels reactive oxygen species capacity antioxidant defense mechanism patients psychiatric disorders factors trigger oxidative cellular damage lipids proteins dna leading abnormal neural growth differentiation therapeutic strategies supplementation antioxidants effective long-term treatment management neuropsychiatric disorders antioxidants pufas supplements treatment neuropsychiatric disorders provided promising results time cautious antioxidants excessive antioxidants dangerously interfere protective functions reactive oxygen species present article give overview potential strategies outcomes antioxidants therapeutics psychiatric disorders
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PLAIN-3474 | MED-1201 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| dietary folate risk depression finnish middle-aged men prospective follow-up study pubmed ncbi abstract background cross-sectional studies focused low blood folate levels depressive patients prospective studies published association dietary folate depression methods studied association dietary folate cobalamin receiving discharge diagnosis depression prospective follow-up setting cohort recruited num num end num consisted num men aged num num years eastern finland results intake folate cohort num microg/day sd num median energy-adjusted folate intake higher risk discharge diagnosis depression rr num num ci num num follow-up period folate intake median excess risk remained significant adjustment current socioeconomic status baseline hpl depression score energy-adjusted daily intake fibre vitamin total fat intake conclusions low dietary intake folate risk factor severe depression nutrition role prevention depression
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PLAIN-3474 | MED-1202 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| low folate risk factor depression meta analysis exploration heterogeneity abstract low folate causatively linked depression research contradictory association arise due chance bias confounding reverse causality systematic review observational studies examined association depression folate conducted num relevant studies num num participants case control studies population surveys cohort study examining risk depression presence low folate found pooling showed significant relationship folate status depression odds ratio or pooled unadjusted num num ci num num relationship remained adjustment potential confounding or pooled adjusted num num ci num num folate levels lower depression accumulating evidence low folate status depression evidence case control cross sectional studies cohort studies definitive randomised controlled trials test therapeutic benefit folate required confirm refute causal relationship
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PLAIN-3474 | MED-1203 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| folic acid supplementation prevention mood disorders young people familial risk randomised double blind placebo controlled trial pubmed ncbi abstract background clinical mood disorders clinically manifest teenage years early twenties poor long-term prognosis primary prevention disorders great public health nutritional supplements feasible intervention primary prevention epidemiological studies links low folate status depressive symptomatology general population method randomised double blind parallel group placebo-controlled trial participants aged num years increased familial risk mood disorder randomised folic acid num mg daily identical placebo liquid maximum num months primary outcome data onset dsm-iv mood disorder collected num participants num group results incidence mood disorder folic acid placebo groups num num non-significant difference post-hoc evidence folic acid delayed time onset mood disorder participants unwell limitations small sample size rate onset mood disorders lower expected conclusions long term folic acid supplementation tolerated high levels adherence evidence reduced incidence mood disorder compared taking placebo copyright num elsevier b v rights reserved
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PLAIN-3474 | MED-1342 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| efficacy paroxetine placebo treating anxiety depression meta-analysis change hamilton rating scales abstract background previous meta-analyses published unpublished trials antidepressants provide modest benefits compared placebo treatment depression argued benefits clinically significant meta-analyses based trials submitted initial fda approval medication limited aimed treating depression time assess efficacy selective serotonin reuptake inhibitor ssri treatment anxiety depression complete data set published unpublished trials sponsored manufacturer methods findings glaxosmithkline required post results sponsored clinical trials online providing opportunity assess efficacy ssri paroxetine complete data set trials conducted examined data placebo-controlled double-blind trials paroxetine included change scores hamilton rating scale anxiety hrsa and/or hamilton rating scale depression hrsd treatment anxiety num efficacy difference paroxetine placebo modest num independent baseline severity anxiety change placebo-treated individuals replicated num magnitude paroxetine response efficacy superior treatment panic disorder num generalized anxiety disorder num published trials showed significantly larger drug-placebo differences unpublished trials num num depression trials num benefit paroxetine placebo consistent previous meta-analyses antidepressant efficacy num conclusions empirical evidence paroxetine modest advantage placebo treatment anxiety depression treatment implications discussed
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PLAIN-3474 | MED-1343 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
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PLAIN-3474 | MED-1344 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| deception treatment case depression pubmed ncbi abstract prescribe placebos patients clinical practice general medical council ambivalent issue american medical association asserts placebos administered patient informed potential problem placebos involve deception case ethical tension arises patient's autonomy physician's requirement open honest notion medical care primary concern paper examines case depression entry point understanding complexities prescription placebos recent important meta-analyses antidepressants claim significantly effective clinical setting placebos antidepressants numerous adverse side effects hugely expensive provocative research potential ethical practical implications patients medical providers placebos prescribed place antidepressants case depression highlights important issue medical ethical codes hitherto overlooked well-being synonymous realistic oneself one's circumstances future severely depressed individuals unduly pessimistic world treatment depressed individuals deemed successful patients successfully attained positive illusions indicative psychological health successful psychological treatments depression achieve limited unavoidable role deception medicine
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PLAIN-3474 | MED-1345 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
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PLAIN-3474 | MED-1355 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| exercise treatment depression anxiety pubmed ncbi abstract depression anxiety common psychiatric conditions general medical setting affecting millions individuals united states treatments depression anxiety multiple varying degrees effectiveness physical activity shown decreased symptoms depression anxiety physical activity consistently shown improved physical health life satisfaction cognitive functioning psychological well-being conversely physical inactivity appears development psychological disorders specific studies support exercise treatment depression exercise compares favorably antidepressant medications first-line treatment mild moderate depression shown improve depressive symptoms adjunct medications extensively studied exercise shown effective cost-efficient treatment alternative variety anxiety disorders effective exercise shown reduce anxiety level achieved psychopharmaceuticals
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PLAIN-3474 | MED-1347 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| antidepressants placebo response pubmed ncbi abstract aims evaluate generation antidepressants relation placebo response methods review meta-analyses response antidepressant medication response placebo calculated results meta-analyses included unpublished published trials trials failed show significant advantage ssris inert placebo differences drug placebo clinically significant depressed patients documents obtained u s food drug administration fda revealed explicit decision information public prescribing physicians conclusions incur drug risks exercise psychotherapy show benefits equal antidepressants treatment choice depressed individuals
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PLAIN-3474 | MED-1348 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| initial severity antidepressant benefits meta-analysis data submitted food drug administration abstract background meta-analyses antidepressant medications reported modest benefits placebo treatment unpublished trial data included benefit falls accepted criteria clinical significance efficacy antidepressants depend severity initial depression scores purpose analysis establish relation baseline severity antidepressant efficacy relevant dataset published unpublished clinical trials methods findings obtained data clinical trials submitted food drug administration fda licensing new-generation antidepressants full datasets meta-analytic techniques assess linear quadratic effects initial severity improvement scores drug placebo groups drug placebo difference scores drug placebo differences increased function initial severity rising virtually difference moderate levels initial depression small difference patients severe depression reaching conventional criteria clinical significance patients upper end severely depressed category meta-regression analyses relation baseline severity improvement curvilinear drug groups showed strong negative linear component placebo groups conclusions drug placebo differences antidepressant efficacy increase function baseline severity small severely depressed patients relationship initial severity antidepressant efficacy attributable decreased responsiveness placebo severely depressed patients increased responsiveness medication editors summary background feels miserable occasionally people depression sad feelings months years interfere daily life depression medical illness caused imbalances brain chemicals regulate mood affects people time life making feel hopeless worthless unmotivated suicidal doctors measure severity depression hamilton rating scale depression hrsd num num item questionnaire answers question score total score questionnaire num severe depression mild depression treated psychotherapy talk therapy cognitive behavioral therapy helps people change negative ways thinking behaving severe depression current treatment combination psychotherapy antidepressant drug hypothesized normalize brain chemicals affect mood antidepressants include tricyclics monoamine oxidases selective serotonin reuptake inhibitors ssris ssris newest antidepressants include fluoxetine venlafaxine nefazodone paroxetine study food drug administration fda uk national institute health clinical excellence nice licensing authorities approved ssris treatment depression doubts remain clinical efficacy antidepressant approved patients undergo clinical trials compare ability improve hrsd scores patients placebo dummy tablet drug individual trial information drug's effectiveness additional information gained combining results trials meta-analysis statistical method combining results studies previously published meta-analysis published unpublished trials ssris submitted fda licensing drugs marginal clinical benefit average ssris improved hrsd score patients num points placebo nice defined significant clinical benefit antidepressants drug placebo difference improvement hrsd score num points average improvement scores obscure beneficial effects groups patient meta-analysis paper researchers investigated baseline severity depression affects antidepressant efficacy researchers find researchers obtained data clinical trials submitted fda licensing fluoxetine venlafaxine nefazodone paroxetine meta-analytic techniques investigate initial severity depression affected hrsd improvement scores drug placebo groups trials confirmed effect generation antidepressants recommended criteria clinical significance showed virtually difference improvement scores drug placebo patients moderate depression small clinically insignificant difference patients severe depression difference improvement antidepressant placebo reached clinical significance patients initial hrsd scores num severely depressed patients additional analyses apparent clinical effectiveness antidepressants severely depressed patients reflected decreased responsiveness placebo increased responsiveness antidepressants findings findings suggest compared placebo new-generation antidepressants produce clinically significant improvements depression patients initially moderate severe depression show significant effects severely depressed patients findings show effect patients due decreased responsiveness placebo increased responsiveness medication results researchers conclude reason prescribe new-generation antidepressant medications severely depressed patients alternative treatments ineffective addition finding extremely depressed patients responsive placebo severely depressed patients similar responses antidepressants potentially important insight patients depression respond antidepressants placebos investigated additional information access web sites online version summary http://dx doi org num journal pmed num
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PLAIN-3474 | MED-1349 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| antidepressants placebo effect abstract antidepressants supposed work fixing chemical imbalance specifically lack serotonin brain supposed effectiveness primary evidence chemical imbalance theory analyses published data unpublished data hidden drug companies reveals benefits due placebo effect antidepressants increase serotonin levels decrease effect serotonin show therapeutic benefit small statistical difference antidepressants placebos enhanced placebo effect due fact patients doctors clinical trials successfully break blind serotonin theory close theory history science proved wrong curing depression popular antidepressants induce biological vulnerability making people depressed future
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PLAIN-3474 | MED-1350 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| pill ill patients reports experience medical encounter treatment depression abstract background starting num broad-based patients rights movement began question doctors paternalism demand disclosure medical information informed consent active participation individual personal health care scholars contributed downplay biomedical approach favor patient-oriented perspective swedish non-profit organization consumer association medicines health kilen offered possibility consumers report perceptions experiences medicines order strengthen consumer rights health care sector methodology paper qualitative content analysis analyze num kilen consumer reports adverse events antidepressant medications order explore patients views mental ill health symptoms doctor-patient interaction principal findings kilen stories contained negative experiences patients medical encounters reports intense emotional outrage strong feelings abuse health care system reports suggested doctors patients accounts nature problems patient seeking patients sought problems tiredness sleeplessness personal crisis sort treating doctor cases exceptionally quick diagnosing depression prescribing antidepressant treatment patients felt listened trust doctor compromised evident cases doctor convince part medical treatment threatening withdraw sick-listing conclusions study suggests dynamics happening medical encounter highly affected medical dominance patient-oriented perspective contribute questionable medicalization and/or pharmaceuticalization depression
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PLAIN-3474 | MED-1351 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
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PLAIN-3474 | MED-1352 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| primum nocere evolutionary analysis antidepressants harm good abstract antidepressant medications first-line treatment people meeting current diagnostic criteria major depressive disorder antidepressants designed perturb mechanisms regulate neurotransmitter serotonin evolutionarily ancient biochemical found plants animals fungi adaptive processes evolved regulated serotonin including emotion development neuronal growth death platelet activation clotting process attention electrolyte balance reproduction principle evolutionary medicine disruption evolved adaptations degrade biological functioning serotonin regulates adaptive processes antidepressants adverse health effects instance antidepressants modestly effective reducing depressive symptoms increase brain susceptibility future episodes discontinued contrary widely held belief psychiatry studies purport show antidepressants promote neurogenesis flawed method distinguish neurogenesis neuronal death fact antidepressants neuronal damage mature neurons revert immature state explain antidepressants neurons undergo apoptosis programmed death antidepressants developmental problems adverse effects sexual romantic life increase risk hyponatremia low sodium blood plasma bleeding stroke death elderly review supports conclusion antidepressants generally harm good disrupting number adaptive processes regulated serotonin specific conditions warranted e g cancer recovery stroke conclude altered informed consent practices greater caution prescription antidepressants warranted
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PLAIN-3474 | MED-1353 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| drugs don work antidepressants current future pharmacological management depression abstract depression potentially life-threatening disorder affecting millions people globe huge burden individual society costing num billion num world health organisation cited leading global disability num developed world project leading num serendipitous discovery antidepressants revolutionized understanding management depression efficacy treatment depression long debated recently brought public limelight controversial publication kirsch role placebo response antidepressant efficacy trials highlighted whilst antidepressants offer benefits short long term important problems persist intolerability delayed therapeutic onset limited efficacy milder depression existence treatment-resistant depression
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PLAIN-3474 | MED-1354 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| antidepressant drug effects depression severity patient-level meta-analysis abstract context antidepressant medications represent established treatment major depressive disorder mdd evidence specific pharmacological effect relative pill-placebo patients severe depression objective estimate relative benefit medication placebo wide range initial symptom severity patients diagnosed depression data sources pubmed psycinfo cochrane library databases searched january num march num references meta-analyses reviews study selection randomized placebo-controlled trials fda approved antidepressants treatment major minor depressive disorder selected studies included authors provided requisite original data comprised adult outpatients included medication placebo comparison num weeks exclude patients basis placebo washout period utilized hamilton rating scale depression data studies num patients included data extraction individual patient-level data obtained study authors results medication placebo differences varied substantially function baseline severity patients hamilton scores num cohen d-type effect sizes difference medication placebo estimated num standard definition small effect estimates magnitude superiority medication placebo increased increases baseline hamilton severity crossed nice threshold clinically significant difference baseline score num conclusions magnitude benefit antidepressant medication compared placebo increases severity depression symptoms minimal nonexistent average patients mild moderate symptoms patients severe depression benefit medications placebo substantial
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PLAIN-3474 | MED-1356 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| association physical activity mental disorders adults united states pubmed ncbi abstract background objective study determine association regular physical activity mental disorders adults united states methods multiple logistic regression analyses compare prevalence mental disorders report regular physical activity data national comorbidity survey num nationally representative sample adults ages num united states conclusions slightly one-half adults reported regular physical activity num regular physical activity significantly decreased prevalence current major depression anxiety disorders significantly affective substance psychotic disorders association regular physical activity lower prevalence current major depression num num num panic attacks num num num social phobia num num num specific phobia num num num agoraphobia num num num persisted adjusting differences sociodemographic characteristics self-reported physical disorders comorbid mental disorders self-reported frequency physical activity showed dose-response relation current mental disorders discussion data document negative association regular physical activity depressive anxiety disorders adults u s population future research investigates mechanism association longitudinal data examine link physical activity incident recurrent mental disorders lifespan needed
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PLAIN-3474 | MED-1357 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| effects exercise training older patients major depression pubmed ncbi abstract background previous observational interventional studies suggested regular physical exercise reduced symptoms depression extent exercise training reduce depressive symptoms older patients major depressive disorder mdd systematically evaluated objective assess effectiveness aerobic exercise program compared standard medication antidepressants treatment mdd older patients conducted num week randomized controlled trial methods hundred fifty-six men women mdd age num years assigned randomly program aerobic exercise antidepressants sertraline hydrochloride combined exercise medication subjects underwent comprehensive evaluations depression including presence severity mdd diagnostic statistical manual mental disorders fourth edition criteria hamilton rating scale depression ham-d beck depression inventory bdi scores treatment secondary outcome measures included aerobic capacity life satisfaction self-esteem anxiety dysfunctional cognitions results num weeks treatment groups differ statistically ham-d bdi scores num adjustment baseline levels depression yielded essentially identical result growth curve models revealed groups exhibited statistically clinically significant reductions ham-d bdi scores patients receiving medication exhibited fastest initial response patients receiving combination therapy severe depressive symptoms initially showed rapid response initially severe depressive symptoms conclusions exercise training program considered alternative antidepressants treatment depression older persons antidepressants facilitate rapid initial therapeutic response exercise num weeks treatment exercise equally effective reducing depression patients mdd
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PLAIN-3474 | MED-1358 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
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PLAIN-3474 | MED-1359 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| physical exercise intervention depressive disorders meta-analysis systematic review pubmed ncbi abstract previous meta-analyses investigating effect exercise depression included trials control condition categorized placebo fact placebo intervention e g meditation relaxation recognized antidepressant effect meditation mindfulness-based interventions depression reduction impossible separate effect physical exercise meditation-related parts present study determined efficacy exercise reducing symptoms depression compared treatment placebo conditions usual care clinically defined depressed adults num retrieved studies num passed inclusion criteria num studies presented sufficient information calculating effect sizes main result showed significant large effect favoring exercise intervention effect size larger trials treatment placebo conditions analyzed effect size reduced moderate level studies high methodological quality included analysis exercise recommended people mild moderate depression motivated physically healthy engage program num john wiley sons a/s published john wiley sons
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PLAIN-3474 | MED-1360 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| exercise pharmacotherapy treatment major depressive disorder abstract objective assess patients receiving aerobic exercise training performed home supervised group setting achieve reductions depression comparable standard antidepressant medication sertraline greater reductions depression compared placebo controls methods october num november num performed prospective randomized controlled trial smile study allocation concealment blinded outcome assessment tertiary care teaching hospital total num adults num women num men diagnosed major depression assigned randomly conditions supervised exercise group setting home-based exercise antidepressant medication sertraline num num mg daily placebo pill num weeks patients underwent structured clinical interview depression completed hamilton depression rating scale ham-d results num months treatment num participants achieved remission defined longer meeting criteria major depressive disorder mdd ham-d score num patients receiving active treatments tended higher remission rates placebo controls supervised exercise num home-based exercise num medication num placebo num num treatment groups lower ham-d scores treatment scores active treatment groups significantly placebo group num conclusions efficacy exercise patients generally comparable patients receiving antidepressant medication tend placebo patients mdd placebo response rates high suggesting considerable portion therapeutic response determined patient expectations ongoing symptom monitoring attention nonspecific factors
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PLAIN-3474 | MED-2750 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| lack benefit dietary advice men angina results controlled trial pubmed ncbi abstract objective mortality men angina reduced dietary advice design randomized controlled factorial trial setting male patients general practitioners south wales subjects total num men num age angina interventions subjects randomly allocated groups num advised eat portions oily fish week fish oil capsules daily num advised eat fruit vegetables oats num types advice num specific dietary advice mortality ascertained num results compliance fish advice fruit advice all-cause mortality reduced form advice effects attributable fruit advice risk cardiac death higher subjects advised oily fish advised adjusted hazard ratio num num confidence interval num num num greater sudden cardiac death num num ci num num num excess risk largely located subgroup fish oil capsules evidence due interactions medication conclusions advice eat fruit poorly complied detectable effect mortality men advised eat oily fish supplied fish oil capsules higher risk cardiac death result unexplained arise risk compensation effect patients doctors behaviour
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PLAIN-3474 | MED-2751 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| global fishmeal fish-oil supply inputs outputs markets pubmed ncbi abstract recent data fishmeal fish-oil supply presented identifying key producer countries raw material sources distinguishing fish by-products conversion raw materials marine ingredients discussed global volumes presented summary main countries marine ingredients recent years fishmeal fish-oil market segment presented global mass balance inputs outputs derived calculation input-to-output ratios fish in:fish fifo main aquaculture production types made current areas focus industry include demonstrate sustainable practice strategic marine ingredients greater fishery land-animal by-products vegetable substitutes sources essential omega num fats notably long-chain polyunsaturated fatty acids eicosapentaenoic epa docosahexaenoic dha acids implications drawn future supply prospects fishmeal fish-oil future role aquaculture agriculture human health num fisheries society british isles
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PLAIN-3474 | MED-2752 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| association omega num fatty acid supplementation risk major cardiovascular disease events systematic review meta-analysis pubmed ncbi abstract context considerable controversy exists association omega num polyunsaturated fatty acids pufas major cardiovascular end points objective assess role omega num supplementation major cardiovascular outcomes data sources medline embase cochrane central register controlled trials august num study selection randomized clinical trials evaluating effect omega num all-cause mortality cardiac death sudden death myocardial infarction stroke data extraction descriptive quantitative information extracted absolute relative risk rr estimates synthesized random-effects model heterogeneity assessed statistic num subgroup analyses performed presence blinding prevention settings patients implantable cardioverter-defibrillators meta-regression analyses performed omega num dose statistical significance threshold num assumed adjustment multiple comparisons data synthesis num citations retrieved num studies num patients included reporting num deaths num cardiac deaths num sudden deaths num myocardial infarctions num strokes statistically significant association observed all-cause mortality rr num num ci num num risk reduction num num ci num num cardiac death rr num num ci num num num num ci num num sudden death rr num num ci num num num num ci num num myocardial infarction rr num num ci num num num num ci num num stroke rr num num ci num num num num ci num num supplement studies considered conclusion omega num pufa supplementation lower risk all-cause mortality cardiac death sudden death myocardial infarction stroke based relative absolute measures association
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PLAIN-3474 | MED-2753 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| secondary prevention chd uk men diet reinfarction trial sequel pubmed ncbi abstract diet reinfarction trial dart involved num men age num years recovering myocardial infarction randomly allocated receive advice receive advice dietary factors increase fatty fish intake reduction fat intake increase polyunsaturated fat:saturated fat increased intake cereal fibre compliance satisfactory fish fibre advice fat advice men fish advice num lower num year all-cause mortality forms advice significant effects diet angina randomized trial dart num involved num men age num years stable angina num years advice eat oily fish fish oil affect all-cause mortality significant increase sudden cardiac death num effect largely confined subgroup fish oil capsules advice eat fruit vegetables effect poor compliance outcome dart num appears conflict dart studies explanations considered nutritional interventions equally acceptable tailored individuals intended distinct groups raised risk chd assumed nutritional interventions nutritional supplements necessarily effects foods derived
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PLAIN-3474 | MED-2754 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| efficacy omega num fatty acid supplements eicosapentaenoic acid docosahexaenoic acid secondary prevention cardiovascular disease pubmed ncbi abstract background previous randomized double-blind placebo-controlled trials reported efficacy omega num fatty acid supplements secondary prevention cardiovascular disease cvd evidence remains inconclusive meta-analysis investigated efficacy eicosapentaenoic acid docosahexaenoic acid secondary prevention cvd methods searched pubmed embase cochrane library april num independently reviewed selected eligible randomized controlled trials results num articles retrieved num randomized double-blind placebo-controlled trials involving num patients history cvd included final analyses supplementation omega num fatty acids reduce risk cardiovascular events relative risk num num ci num num all-cause mortality sudden cardiac death myocardial infarction congestive heart failure transient ischemic attack stroke small reduction cardiovascular death relative risk num num ci num num disappeared excluded study major methodological problems significant preventive effect observed subgroup analyses country location inland coastal geographic area history cvd concomitant medication type placebo material trial methodological quality trial duration treatment dosage eicosapentaenoic acid docosahexaenoic acid fish oil supplementation treatment conclusion meta-analysis showed insufficient evidence secondary preventive effect omega num fatty acid supplements cardiovascular events patients history cardiovascular disease
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PLAIN-3474 | MED-2755 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| effects fat fish fibre intakes death myocardial reinfarction diet reinfarction trial dart pubmed ncbi abstract randomised controlled trial factorial design examine effects dietary intervention secondary prevention myocardial infarction mi num men recovered mi allocated receive receive advice dietary factors reduction fat intake increase ratio polyunsaturated saturated fat increase fatty fish intake increase cereal fibre intake advice fat difference mortality produced small reduction num serum cholesterol subjects advised eat fatty fish num reduction num year all-cause mortality compared advised effect significant altered adjusting ten potential confounding factors subjects fibre advice slightly higher mortality subjects significant num year incidence reinfarction death ischaemic heart disease significantly affected dietary regimens modest intake fatty fish portions week reduce mortality men recovered mi
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PLAIN-3474 | MED-2756 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| fish consumption omega num fatty acids environmental contaminants relation low-grade inflammation early atherosclerosis pubmed ncbi abstract background fish consumption omega num polyunsaturated fatty acid pufa intake shown protect cardiovascular diseases cvd fish environmental contaminants dibenzo-p-dioxins dibenzofurans pcdd/fs polychlorinated biphenyls pcbs methylmercury mehg adverse effects cardiovascular health objective aim elucidate associations fish consumption omega num pufas environmental contaminants low-grade inflammation early atherosclerosis traditional cvd risk factors methods health num survey participants num represented general finnish population fishermen study participants num represented population high fish consumption high exposure environmental contaminants model-adjusted geometric means tests linear trend calculated cvd risk factors tertiles fish consumption serum omega num pufas additionally fishermen study tertiles serum pcdd/f+pcb blood mehg results serum triglyceride decreased omega num pufa tertiles sexes studies insulin resistance c-reactive protein tumour necrosis factor interleukin num decreased omega num pufa tertiles health num survey participants fishermen study men insulin resistance arterial stiffness stiffness index tended increase rr estimate carotid artery plaque tended decrease tertiles pcdd/f+pcb mehg conclusion previously established hypotriglyceridemic anti-inflammatory effects omega num pufas study hypothesised favourable effect insulin sensitivity arterial elasticity suggested counteracted high exposure environmental contaminants effect plaque prevalence appeared harmful copyright num elsevier rights reserved
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PLAIN-3474 | MED-3021 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| hair-to-blood ratio biological half-life mercury experimental study methylmercury exposure fish consumption humans pubmed ncbi abstract hair-to-blood ratio biological half-life methylmercury one-compartment model differ past recent studies reevaluate num healthy volunteers exposed methylmercury provisional tolerable weekly intake num g/kg body weight/week adults fish consumption num weeks num week washout period cessation exposure blood collected num num weeks hair cut num weeks total mercury t-hg concentrations analyzed blood hair t-hg levels blood hair changed time num concentrations increased num ng/g week num num ng/g week num blood num num g/g hair hair-to-blood ratio adjustment time lag blood hair num num s d entire period half-lives t-hg calculated raw data num num days blood num num days hair half-lives recalculated subtracting background levels raw data num num num num days conclusion hair-to-blood ratio methylmercury based past studies appears underestimated light recent studies crude half-life preferred recalculated practicability uncertainties background level half-life approximate conventional
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PLAIN-3474 | MED-3023 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| relationship prenatal exposure low-level mercury size newborn's cerebellum pubmed ncbi abstract exposure methylmercury stage central nervous system development induce alterations result severe congenital abnormalities total mercury level maternal hair pregnancy correlates blood levels methylmercury total mercury levels fetal brain prospective study conducted total num childbearing women living coastal region term normal pregnancies included newborns evaluated ultrasonography mothers newborns divided groups hair mercury levels examined group high body levels mercury num g/g control group low body levels mercury num g/g neurosonographic examination conducted newborns dimensions cerebellum sagital-medial plane measured maximum height width starting roof fourth chamber majority mothers hair mercury levels lower num g/g num num g/g sd num ranging num num g/g significant difference groups width cerebellum mann-whitney test num num comparison related length cerebellum shows statistically significant smaller cerebellum newborns mother hair mercury levels higher num g/g mann-whitney test num num results lead conclusion prenatal exposure low-levels methylmercury influence fetal brain development detected decreased size newborn's cerebellum clinical point view question related influence prenatal low-level methylmercury exposure fetal neurodevelopment remains open objectives direct research performing detailed neuropshychological tests children age num months tests presence subtle neurological neuropsychological deficits copyright num elsevier rights reserved
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PLAIN-3474 | MED-2904 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| dose response relationship prenatal mercury exposure iq integrative analysis epidemiologic data abstract background prenatal exposure mercury adverse childhood neurologic outcomes epidemiologic studies dose response information relationship estimating benefits reduced mercury exposure objectives estimated dose response relationship maternal mercury body burden subsequent childhood decrements intelligence quotient iq bayesian hierarchical model integrate data epidemiologic studies methods inputs model consist dose response coefficients studies conducted faroe islands zealand seychelles islands iq coefficients previous work studies coefficient faroe islands study estimated iq subtests tests cognition/achievement included hierarchical model obtain accurate estimates study-to-study end point end point variability results find central estimate num iq points num confidence interval num num parts million increase maternal hair mercury similar estimates faroe islands seychelles studies lower magnitude estimate zealand study sensitivity analyses produce similar results iq coefficient central estimate ranging num num conclusions iq end point estimating neurodevelopmental effects fully represent cognitive deficits mercury exposure represent deficits related attention motor skills integrated iq coefficient robust description dose response relationship prenatal mercury exposure cognitive functioning results single study
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PLAIN-3474 | MED-2905 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| associations maternal long chain polyunsaturated fatty acids methyl mercury infant development seychelles child development nutrition study abstract fish consumption gestation provide fetus long chain polyunsaturated fatty acids lcpufa nutrients essential growth development brain fish consumption exposes fetus neurotoxicant methyl mercury mehg studied association fetal exposures early child development seychelles child development nutrition study scdns specifically examined priori models num num lcpufa measures maternal serum test hypothesis lcpufa families adjusting prenatal mehg exposure reveal associations child development assessed bsid-ii ages num num months num children complete outcome covariate data analysis num months pdi positively total num lcpufa negatively ratio num num lcpufa associations stronger models adjusted prenatal mehg exposure secondary models suggested mehg effect num months varied ratio num num lcpufa significant associations lcpufa measures pdi num months significant adverse associations prenatal mehg num month pdi lcpufa measures included regression analysis bsid-ii mental developmental index mdi exposure variable data support potential importance child development prenatal availability num lcpufa present fish lcpufa diet beneficial effects lcpufa obscure determination adverse effects prenatal mehg exposure longitudinal observational studies
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PLAIN-3474 | MED-2906 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| speciation methyl ethyl-mercury hair breastfed infants acutely exposed thimerosal-containing vaccines pubmed ncbi abstract background chemical forms mercury occur naturally human milk controversial aspect early post-natal exposure organic mercury ethylmercury ethg thimerosal-containing vaccines tcv countries exclusively breastfed infants exposed fish derived methylmercury mehg maternal diets ethg tcv aim study evaluate analytical method ethyl methyl mercury hair samples breastfed infants received recommended schedule tcv methods hair infants num months exposed tcv hepatitis dtap analysed method coupling isothermal gas chromatography cold-vapor atomic fluorescence spectrometry mehg speciate ethg biological matrices results num samples infants hair samples showed variable amounts mehg num num ng/g precise reliable concentrations ethg num num ng/g found num num samples statistically significant inverse association num num found hair-ethg concentrations time elapsed tcv shot conclusions analytical method proved sensitive quantify ethg babies hair acute exposure thimerosal vaccine shots provided mass hair num organic-mercury exposure early life speciated quantified babies hair opening opportunities clinical forensic studies copyright num elsevier b v rights reserved
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PLAIN-3474 | MED-2907 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| fish eat perspectives influencing fish consumption choices abstract background diverse perspectives influenced fish consumption choices objectives summarized issue fish consumption choice toxicological nutritional ecological economic points view identified areas overlap disagreement viewpoints reviewed effects previous fish consumption advisories methods reviewed published scientific literature public health guidelines advisories related fish consumption focusing advisories targeted u s populations conclusions apply groups similar fish consumption patterns discussion combinations matters related fish consumption fish consumption patterns optimize domains fish rich source protein nutrients contamination methylmercury toxicants higher fish intake leads greater toxicant exposure stocks wild fish adequate meet nutrient demands growing world population fish consumption choices broad economic impact fishing industry guidance account ecological economic impacts fish consumption choices conclusion relative lack information integrating health ecological economic impacts fish choices clear simple guidance effect desired comprehensive advice developed describe multiple impacts fish consumption addition policy fishery management inter-ventions ensure long-term availability fish important source human nutrition
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PLAIN-3474 | MED-3024 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| dietary lipids modulate methylmercury toxicity atlantic salmon pubmed ncbi abstract experiment aimed study molecular toxicity methylmercury mehg liver brain white muscle atlantic salmon fed diet based fish oil fo high dietary num num ratio compared alternative diet based vegetable oil vo low dietary num num ratio juvenile salmon fed decontaminated diets fo vo diets enriched num mg hg/kg added mehg months dietary lipid composition affected fatty acid composition tissues liver white muscle num days exposure liver accumulated times mehg brain white muscle vitamin content heme oxygenase tubulin alpha tuba cpt num transcriptional levels showed significant effects mehg exposure liver tbars tocopherol tocopherol transcriptional levels thioredoxin heme oxygenase tuba pparb num num num showed effect dietary lipid composition liver tissue effects dietary lipids observed brain tissue mt-a hif num bcl-x tuba interaction effects mehg exposure dietary lipid composition observed tissues data suggest dietary fats modulating effects mehg toxicity atlantic salmon copyright num elsevier rights reserved
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PLAIN-3474 | MED-3025 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| abnormal neuronal migration deranged cerebral cortical organization diffuse white matter astrocytosis human fetal brain major effect pubmed ncbi abstract detailed clinical neuropathological studies made fullterm newborn human infants exposed methylmercury utero result maternal ingestion methylmercury-contaminated bread early phases pregnancy high levels mercury detected regions brain autopsy study brains revealed disturbance development cases consisting essentially incomplete abnormal migration neurons cerebellar cerebral cortices deranged cortical organization cerebrum numerous heterotopic neurons isolated groups white matter cerebrum cerebellum laminar cortical pattern laminar cortical pattern cerebrum disturbed regions shown irregular groupings deranged alignment cortical prominent white matter cerebrum cerebellum diffuse gemistocytic astrocytosis accompanied accumulation mercury grains cytoplasm findings high degree vulnerability human fetal brain maternal intoxication methylmercury major effect appears related faulty development destructive focal neuronal damage observed mercury intoxicaiton adults children exposed postnatally
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PLAIN-3474 | MED-2910 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| sensitivity continuous performance test cpt age num years developmental methylmercury exposure abstract hit reaction time latencies hrt continuous performance test cpt measure speed visual information processing latencies involve neuropsychological functions depending time test initiation i e orientation learning habituation cognitive processing focused attention finally sustained attention dominant demand prenatal methylmercury exposure increased reaction time rt latencies examined association methylmercury exposure average hrt age num years time intervals test initiation total num adolescents num birth cohort members completed cpt rt latencies recorded num minutes visual targets presented num ms intervals confounder adjustment regression coefficients showed cpt-rt outcomes differed associations exposure biomarkers prenatal methylmercury exposure minutes average hrt weakly methylmercury beta se ten-fold increase exposure num num strongly num num minute interval num num strongest num num minutes test initiation num num pattern unchanged simple reaction time finger tapping speed included models covariates postnatal methylmercury exposures affect outcomes findings suggest sustained attention neuropsychological domain vulnerable developmental methylmercury exposure indicating probable underlying dysfunction frontal lobes cpt data measure neurotoxicity test results analyzed regard time test initiation average reaction times
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PLAIN-3474 | MED-3027 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| marine food pollutants risk factor hypoinsulinemia type num diabetes abstract background persistent environmental chemicals suspected causing increased risk type num diabetes mellitus disease common age num concern examined cross-sectional study elderly subjects population elevated contaminant exposures seafood species high food chain methods clinical examinations num faroese residents aged num years num eligible population included fasting plasma concentrations glucose insulin glycosylated hemoglobin lifetime exposure persistent environmental chemicals pilot whale traditional food estimated dietary questionnaire analysis blood samples polychlorinated biphenyls pcbs related food contaminants results septuagenarians type num diabetes impaired fasting glycemia tended higher pcb concentrations higher past intake traditional foods childhood adolescence non-diabetic subjects fasting insulin concentration decreased num ci num num doubling pcb concentration adjustment sex body mass index age num conversely fasting glucose concentration increased num num num doubling pcb similar associations subjects impaired fasting glycemia adjustment current body mass index lipid metabolism parameters attenuated associations conclusions impaired insulin secretion appears constitute important part type num diabetes pathogenesis exposure persistent lipophilic food contaminants
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PLAIN-3474 | MED-3028 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| fish consumption dietary long-chain num fatty acids risk type num diabetes abstract objective evidence association fish consumption dietary long-chain num fatty acids risk type num diabetes inconsistent performed systematic review meta-analysis prospective evidence research design methods studies identified searching pubmed embase databases num december num reviewing reference lists retrieved articles prospective studies included reported relative risk rr estimates num cis association fish consumption and/or dietary long-chain num fatty acids incidence type num diabetes dose-response random-effects model combine study-specific rrs potential sources heterogeneity explored prespecified stratifications results sixteen studies involving num participants num diabetes cases included considerable statistical heterogeneity summary estimates partly explained geographical differences serving week increment fish consumption rrs num cis type num diabetes num num num num num num num num num combining u s european asian/australian studies num day increment long-chain num fatty acids summary estimates num num num num num num num num num conclusions results meta-analysis differences geographical regions observed associations fish consumption dietary intake long-chain num fatty acids risk type num diabetes consideration heterogeneous results relationship warrants investigation current public health recommendations fish consumption upheld unchanged
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PLAIN-3474 | MED-2913 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| elimination half-lives polychlorinated biphenyl congeners children abstract elimination kinetics polychlorinated biphenyls pcbs humans difficult assess observational studies pcb exposure completely abolished community high dietary pcb exposures whale blubber examined groups children increased body burdens breast-feeding follow-up ages num years num years num subjects num num years num subjects calculations performed structural equation models adjustment body weight dietary blubber intake main source postnatal exposure result background exposures apparent elimination half-lives unexpectedly long based results cohort members subjects exposures median highest quartile showed half-lives num years cb num num num years cb num cb num num num years cb num cb num cb num num years cb num cb num longest half-lives correspond elimination parent pcb solely daily fat excretion rate num shorter half-lives assume metabolic break-down
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PLAIN-3474 | MED-3012 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| fish consumption child bearing age quantitative risk-benefit analysis neurodevelopment pubmed ncbi abstract fish ingredient num docosahexaenoic acid num num dha stimulates brain development hand methylmercury mehg fish disturbs developing central nervous system context iq score children considered aggregate measure utero brain development determine effect dha exposure prenatal neurodevelopment maternal dha intake pregnancy compared epidemiologically observed effect iq score children mehg maternal intake converted accumulation maternal body maternal body burden compared epidemiologically observed relationship iq score taking mehg dha content num fish species net effect compounds iq score quantified fish species adverse effect mehg iq score exceeded beneficial effect dha case long-living predators negative effect num points iq score found results study food interventions aiming beneficial effects fish consumption focus fish species high dha content avoiding fish species high mehg content copyright num elsevier rights reserved
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PLAIN-3474 | MED-3013 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
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PLAIN-3474 | MED-3030 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| national advisories serve local consumers assessment mercury economically important north carolina fish pubmed ncbi abstract consumption marine fish benefits lean protein omega num fatty acids essential nutrients risks main source mercury hg exposure humans mercury potent neurotoxin source fish advisories nationwide toxicant widespread nature hg unknown local hg contamination reflects national regional levels bases inform consumers potential fish consumption risk objectives study examine hg levels commonly consumed marine species harvested locally north carolina coast compare results published regional monterey bay aquarium's seafood watch list national environmental protection agency epa food drug administration fda hg averages action levels guidelines found significant differences hg concentrations collected species identified correlations hg concentration fish length trophic levels collected mahi mahi triggerfish epa fish tissue action level num ppm wahoo grouper exceeded epa action level fda action level num ppm king mackerel highest hg concentration targeted species exceeding epa fda action levels local results consistent calculated averages epa fda databases species findings consistent monterey bay aquarium's seafood watch list southeast region recommendations based hg levels conflict recommendations provide based sustainability find regional national averages reflective local hg contamination suggest local data needed accurately assess consumer risk
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PLAIN-3474 | MED-2917 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| nutrients contaminants human milk mothers macrobiotic omnivorous diets pubmed ncbi abstract effect alternative dietary habits prolonged lactation nutrient contaminant concentrations human milk studied study sample consisted mothers macrobiotic diets diary products meat num months postpartum num num months postpartum num mothers omnivorous diets num months postpartum num protein zinc concentrations breast-milk macrobiotic mothers decreased stage lactation adjustment stage lactation milk macrobiotic mothers contained calcium magnesium saturated fatty acids num num polyunsaturated fatty acids observed tendencies lower protein fat higher lactose concentrations macrobiotic group statistically significant concentrations vitamin num hcb polychlorinated biphenyls pcb num pcb num pcb num pcb num lower macrobiotic group adjustment confounding variables meat fish consumption dairy products contributed vitamin num concentrations meat diary products strongly contributed breast-milk concentrations dieldrin pcbs fish pcb num smoking ddt dieldrin findings suggest breast-milk contamination reduced abstinence smoking moderate intake animal products risk nutritional deficiencies rules complete avoidance meat fish diary products quantitative research effects reduced consumption animal products smoking breast-milk contamination warranted
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PLAIN-3474 | MED-3033 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| smoking lung cancer risk american japanese men international case-control study pubmed ncbi abstract rates lung cancer american men greatly exceeded japanese men decades higher smoking prevalence japanese men relative risk lung cancer cigarette smoking lower japanese men american men risks vary amount duration smoking estimate smoking-specific relative risks lung cancer men multicentric case-control study carried york city washington dc nagoya japan num num total num cases num age-matched controls interviewed united states hospitals num cases num hospital controls japanese hospitals num japanese age-matched healthy controls randomly selected electoral rolls odds ratio lung cancer current united states smokers relative nonsmokers num num confidence interval ci num num num times higher num current smokers japanese relative hospital controls num ci num num times higher japanese relative community controls num num ci num num substantial differences number years smoking average daily number cigarettes smoked united states japanese cases united states japanese controls american cases began smoking average num years earlier japanese cases risk lung cancer cigarette smoking substantially higher united states japanese males consistent population-based statistics smoking prevalence lung cancer incidence explanations difference risk include toxic cigarette formulation american manufactured cigarettes evidenced higher concentrations tobacco-specific nitrosamines tobacco mainstream smoke wider activated charcoal filters japanese american cigarettes documented differences genetic susceptibility lifestyle factors smoking
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PLAIN-3474 | MED-3034 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| awareness knowledge methylmercury fish united states pubmed ncbi abstract num states great lakes region concerned mercury contamination lakes rivers issue local fish consumption advisories num food drug administration fda advised pregnant women nursing mothers young children women pregnant consume shark swordfish king mackerel tilefish recommended women exceed num ounces fish week num fda reissued advice jointly u s environmental protection agency epa modified slightly provide information consumption canned tuna details consumption recreationally caught fish studies examined consumers awareness joint fda epa advisory state advisories representative data examined awareness knowledge mercury problem fish pooled nationally representative num num food safety surveys fss sample sizes num num num num results increase consumers awareness mercury problem fish num num num num num regression models found years parents children num years age aware mercury fish knowledgeable information contained national advisories mercury fish num adults num num women childbearing age aged num aware knowledgeable information women women age groups larger gains awareness knowledge male counterparts time participants race education income region fish preparation experiences foodborne illness past year risk perceptions safety food significant predictors awareness knowledge copyright num elsevier rights reserved
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PLAIN-3474 | MED-3035 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| functional mri approach developmental methylmercury polychlorinated biphenyl neurotoxicity abstract prenatal early childhood exposure methylmercury mehg polychlorinated biphenyls pcbs deficits cognitive sensory motor functions measured neurobehavioral tests main objective pilot study determine functional magnetic resonance imaging fmri effective visualization brain function alterations related neurobehavior subjects high prenatal exposure neurotoxicants mehg pcbs twelve adolescents boys faroese birth cohort assembled num num recruited based prenatal exposures mehg pcb underwent fmri scanning behavioral tasks age num years subjects high mixed exposure mehg pcbs compared low mixed exposure fmri photic stimulation motor task boys low mixed exposures showed patterns fmri activation visual motor tasks typical normal control subjects high exposures showed activation areas brain wider patterns activation low mixed exposure group brain activation patterns observed association increased exposures mehg pcbs meaningful regard neurotoxicity substances methodology potential utility visualizing structural neural system determinants exposure-induced neurobehavioral dysfunction
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PLAIN-3474 | MED-2921 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| evidence human health effects low-level methylmercury exposure abstract background methylmercury mehg neuro-toxicant emerging evidence adverse effects neuro-logic body systems common low levels exposure impacts mehg exposure vary individual susceptibility confounded bene-ficial nutrients fish mehg global relevance synthesis literature low-level mehg exposure limited objectives undertook synthesis current knowledge human health effects low-level mehg exposure provide basis future research efforts risk assessment exposure remediation policies worldwide data sources extraction reviewed published literature original human epidemio-logic research articles reported direct biomarker mercury exposure focus high-quality studies specifically low mercury exposure excluded case series studies populations unusually high fish consumption e g seychelles marine mammal consumption e g faroe islands circumpolar indigenous populations consumption highly contaminated fish e g gold-mining regions amazon data synthesis recent evidence raises possibility effects low-level mehg exposure fetal growth susceptible subgroups infant growth num years life low-level effects mehg neuro-logic outcomes differ age sex timing exposure clear pattern observed cardio-vascular disease cvd risk populations specific cvd end points studies evaluating immunologic effects mehg results inconsistent conclusions studies targeted identifying potential mechanisms low-level mehg effects characterizing individual susceptibility sexual dimorphism non-linearity dose response guide future prevention policy regulatory efforts surrounding mehg exposure
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PLAIN-3474 | MED-3019 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| evidence human health effects low-level methylmercury exposure abstract background methylmercury mehg neuro-toxicant emerging evidence adverse effects neuro-logic body systems common low levels exposure impacts mehg exposure vary individual susceptibility confounded bene-ficial nutrients fish mehg global relevance synthesis literature low-level mehg exposure limited objectives undertook synthesis current knowledge human health effects low-level mehg exposure provide basis future research efforts risk assessment exposure remediation policies worldwide data sources extraction reviewed published literature original human epidemio-logic research articles reported direct biomarker mercury exposure focus high-quality studies specifically low mercury exposure excluded case series studies populations unusually high fish consumption e g seychelles marine mammal consumption e g faroe islands circumpolar indigenous populations consumption highly contaminated fish e g gold-mining regions amazon data synthesis recent evidence raises possibility effects low-level mehg exposure fetal growth susceptible subgroups infant growth num years life low-level effects mehg neuro-logic outcomes differ age sex timing exposure clear pattern observed cardio-vascular disease cvd risk populations specific cvd end points studies evaluating immunologic effects mehg results inconsistent conclusions studies targeted identifying potential mechanisms low-level mehg effects characterizing individual susceptibility sexual dimorphism non-linearity dose response guide future prevention policy regulatory efforts surrounding mehg exposure
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PLAIN-3474 | MED-3022 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| faces methylmercury poisoning pubmed ncbi abstract methylmercury mm potent neurotoxic agent role polluting environment documented vast amount study past decades finally provided insight aspects effect exposure mm ingestion poisoned fish inadvertent misuse grain treated poison fungicide major epidemics occurred japan fetal minamata disease iraq pakistan guatemala ghana sporadic incidences occurred united states canada effective antidote counteract effect mm central nervous system information documented provide hope effective therapy acute cases
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PLAIN-3474 | MED-3026 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| dose response relationship prenatal mercury exposure iq integrative analysis epidemiologic data abstract background prenatal exposure mercury adverse childhood neurologic outcomes epidemiologic studies dose response information relationship estimating benefits reduced mercury exposure objectives estimated dose response relationship maternal mercury body burden subsequent childhood decrements intelligence quotient iq bayesian hierarchical model integrate data epidemiologic studies methods inputs model consist dose response coefficients studies conducted faroe islands zealand seychelles islands iq coefficients previous work studies coefficient faroe islands study estimated iq subtests tests cognition/achievement included hierarchical model obtain accurate estimates study-to-study end point end point variability results find central estimate num iq points num confidence interval num num parts million increase maternal hair mercury similar estimates faroe islands seychelles studies lower magnitude estimate zealand study sensitivity analyses produce similar results iq coefficient central estimate ranging num num conclusions iq end point estimating neurodevelopmental effects fully represent cognitive deficits mercury exposure represent deficits related attention motor skills integrated iq coefficient robust description dose response relationship prenatal mercury exposure cognitive functioning results single study
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PLAIN-3474 | MED-3029 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| fish eat perspectives influencing fish consumption choices abstract background diverse perspectives influenced fish consumption choices objectives summarized issue fish consumption choice toxicological nutritional ecological economic points view identified areas overlap disagreement viewpoints reviewed effects previous fish consumption advisories methods reviewed published scientific literature public health guidelines advisories related fish consumption focusing advisories targeted u s populations conclusions apply groups similar fish consumption patterns discussion combinations matters related fish consumption fish consumption patterns optimize domains fish rich source protein nutrients contamination methylmercury toxicants higher fish intake leads greater toxicant exposure stocks wild fish adequate meet nutrient demands growing world population fish consumption choices broad economic impact fishing industry guidance account ecological economic impacts fish consumption choices conclusion relative lack information integrating health ecological economic impacts fish choices clear simple guidance effect desired comprehensive advice developed describe multiple impacts fish consumption addition policy fishery management inter-ventions ensure long-term availability fish important source human nutrition
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PLAIN-3474 | MED-3032 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| associations maternal long chain polyunsaturated fatty acids methyl mercury infant development seychelles child development nutrition study abstract fish consumption gestation provide fetus long chain polyunsaturated fatty acids lcpufa nutrients essential growth development brain fish consumption exposes fetus neurotoxicant methyl mercury mehg studied association fetal exposures early child development seychelles child development nutrition study scdns specifically examined priori models num num lcpufa measures maternal serum test hypothesis lcpufa families adjusting prenatal mehg exposure reveal associations child development assessed bsid-ii ages num num months num children complete outcome covariate data analysis num months pdi positively total num lcpufa negatively ratio num num lcpufa associations stronger models adjusted prenatal mehg exposure secondary models suggested mehg effect num months varied ratio num num lcpufa significant associations lcpufa measures pdi num months significant adverse associations prenatal mehg num month pdi lcpufa measures included regression analysis bsid-ii mental developmental index mdi exposure variable data support potential importance child development prenatal availability num lcpufa present fish lcpufa diet beneficial effects lcpufa obscure determination adverse effects prenatal mehg exposure longitudinal observational studies
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PLAIN-3474 | MED-3020 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| analysis autopsy brain tissue infants prenatally exposed methymercury pubmed ncbi abstract brains num neonatal autopsies seychelles examined histologically analyzed mercury levels brain regions sampled frontal occipital cortex temporal cortex hippocampus basal ganglia thalamus cerebellum pons medulla tissue blocks histology mercury analysis opposing faces provide correlation findings similar studies performed num reference neonatal brains rochester york clear-cut developmental abnormality found brains exhibited low-grade non-specific destructive total mercury levels organic form elevated seychelles specimens correlation demonstrated mercury levels degree type histologic change considerable variability total mercury anatomic region num seychelles cases region individual brains values total mercury num ppb statistical analysis mercury levels region demonstrated higher values deep subcortical nuclei brain stem cerebellum phylogenetically older parts brain total mercury concentration region paired areas brain paired values plotted entire group brains high correlations obtained brain pairs suggesting strong concentration-dependent relationship mercury intake brain content analysis mercury levels separately dissected blocks grey white matter num specimens revealed significant differences grey white comparison human developmental studies experimental developmental studies animals toxicity demonstrated total mercury brain levels num ppb study found evidence toxicity range mercury levels num ppb submicroscopic subcellular alterations subtle disturbances unfolding brain architectonics excluded methods report studies threshold effects mehg fetal brain essential approximately half mercury resides glial elements white matter reinforces focus attention glia neurons development
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PLAIN-3474 | MED-3031 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| quantitative synthesis mercury commercial seafood implications exposure united states abstract background mercury hg toxic metal presents public health risks fish consumption major source uncertainty evaluating harmful exposure inadequate knowledge hg concentrations commercially important seafood objectives examined patterns variability knowledge gaps hg common commercial seafood items united states compared seafood hg concentrations database exposure estimates consumption advice methods developed database hg concentrations fish shellfish common u s market aggregating data government monitoring programs scientific literature calculated grand individual seafood items based reported means individual studies weighted sample size compared database results federal programs human health criteria u s food drug administration hg monitoring program fda-mp u s environmental protection agency epa results hg concentrations seafood item highly variable studies spanning num num orders magnitude farmed fish generally lower grand hg concentrations wild counterparts wild seafood num num fold higher concentrations depending seafood item farmed fish understudied specific seafood items seafood imports asia south america finally found large discrepancies hg concentrations estimated database fda-mp estimates seafood items examined conclusions high variability hg common seafood items considerable ramifications public health formulation consumption guidelines exposure risk analyses derived smaller data sets reflect collective information seafood hg concentrations
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PLAIN-3474 | MED-3540 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| monoaminergic neurotransmission history discovery antidepressants num today pubmed ncbi abstract num clinical introduction specifically antidepressant drugs iproniazid monoamine-oxidase inhibitor treatment tuberculosis imipramine drug tricyclic antidepressant family iproniazid imipramine made fundamental contributions development psychiatry social-health nature consisting authentic change psychiatric care depressive patients purely pharmacological nature agents constituted indispensable research tool neurobiology psychopharmacology permitting things postulation aetiopathogenic hypotheses depressive disorders clinical introduction fluoxetine selective serotonin reuptake inhibitor late num revolutionized therapy depression opening families antidepressants present work reviews historical perspective entire process led discovery drugs contribution development neuroscientific disciplines antidepressants rest clinical practice share action mechanism involves modulation monoaminergic neurotransmission synaptic level future antidepressant therapy revolve search extraneuronal non-aminergic mechanisms mechanisms modulate intraneuronal biochemical pathways
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PLAIN-3474 | MED-3541 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| frequent consumption vegetables predicts lower risk depression older taiwanese results prospective population-based study pubmed ncbi abstract objective study evaluated association consumption frequencies major food categories risk depression years older taiwanese design prospective cohort study multistage random sampling logistic regression analysis evaluated significance longitudinal associations intake frequencies major food categories future num years risk depression controlled confounding factors adjustment cognitive status setting population-based free-living elderly subjects men women num num years age results regression model controlled demographic socio-economic lifestyle disease/health-related variables cognitive status fruits num num ci num num num num num vegetables num num ci num num num num num protective depressive symptoms num years regression model adjusted cognitive status vegetables num num ci num num num num num protective depressive symptoms higher consumption eggs close significant regression models num num num num food categories including meat/poultry fish seafood dairy legumes grains tea showed significant associations conclusions results suggest confounding factors totally ruled frequent consumption vegetables protective depressive symptoms elderly studies needed elucidate causal role mechanism association
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PLAIN-3474 | MED-3542 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| monoamine oxidase inhibitors cheese effect pubmed ncbi abstract behavior inhibitors monoamine oxidase-a mao-a considered terms possibility effective antidepressant give rise hypertensive interactions dietary tyramine studies punch-biopsy samples human intestine rat intestinal samples show mao-a predominant form enzyme species transport studies everted rat intestinal preparations tyramine extensively metabolized transport intestine selective inhibition mao-a clorgyline results large increase amount unchanged tyramine transported selective inhibition mao-b l-deprenyl selegiline significant effect behavior reversible mao-a inhibitors significantly reduce eliminate effects intestinal metabolism tyramine inhibition competitive nature
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PLAIN-3474 | MED-3543 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| dietary inhibitors monoamine oxidase pubmed ncbi abstract inhibition monoamine oxidase treat depression anxiety information pharmacokinetics flavonoids components tobacco prompted exploration healthy diet smoking active compounds amounts sufficient partially inhibit monoamine oxidase literature search identify dietary monoamine oxidase inhibitors levels compounds foods pharmacokinetics absorption distribution tissue levels observed estimated daily intake expected tissue concentrations compared measured efficacies compounds inhibitors monoamine oxidases norharman harman quercetin dietary presence pharmacokinetics tissue levels consistent significant levels reaching neuronal monoamine oxidase diet smoking num num tetrahydroisoquinoline eugenol num piperoylpiperidine coumarin quercetin equipotent norharman monoamine oxidase inhibitor metabolite isorhamnetin inhibits total quercetin highest compounds sample diet bioavailability variable depending source healthy diet amounts quercetin give sufficient amounts brain induce monoamine oxidase inhibition small decrease neurotransmitter breakdown
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PLAIN-3474 | MED-3544 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| contribution monoamine oxidase mao inhibition tobacco alcohol addiction pubmed ncbi abstract whole-body pet-scan studies brains tobacco smokers shown decrease monoamine oxidase mao activity reverts control level quit smoking observed decrease mao activity smokers due exposure tobacco constituents possess mao-inhibiting properties inhibition mao activity unique feature tobacco smoking subjects type ii alcoholism reported show similar decrease mao activity reverses cease alcohol present review summarizes data mao-inhibiting tobacco constituents explains decrease mao activity observed alcoholics due concomitant tobacco concluded inhibition mao constituents contained tobacco tobacco smoke enhances addiction induced tobacco smoking
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PLAIN-3474 | MED-3545 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| restriction meat fish poultry omnivores improves mood pilot randomized controlled trial abstract background omnivorous diets high arachidonic acid aa compared vegetarian diets research shows high intakes aa promote brain disturb mood omnivores eat fish regularly increase intakes eicosapentaenoic acid epa docosahexaenoic acid dha fats oppose negative effects aa vivo recent cross-sectional study omnivores reported significantly worse mood vegetarians higher intakes epa dha study investigated impact restricting meat fish poultry mood findings thirty-nine omnivores randomly assigned control group consuming meat fish poultry daily omn group consuming fish num times weekly avoiding meat poultry fish vegetarian group avoiding meat fish poultry veg baseline weeks participants completed food frequency questionnaire profile mood states questionnaire depression anxiety stress scales diet intervention veg participants reduced epa dha aa intakes fish participants increased epa dha intakes mood scores unchanged omn fish participants mood scores veg participants improved significantly weeks conclusions restricting meat fish poultry improved domains short-term mood state modern omnivores knowledge trial examine impact restricting meat fish poultry mood state omnivores
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PLAIN-3474 | MED-3546 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| elevated monoamine oxidase levels brain explanation monoamine imbalance major depression pubmed ncbi abstract context monoamine theory depression proposes monoamine levels lowered explanation monoamine loss occurs monoamine oxidase mao-a enzyme metabolizes monoamines serotonin norepinephrine dopamine objective determine mao-a levels brain elevated untreated depression setting tertiary care psychiatric hospital patients seventeen healthy num depressed individuals major depressive disorder met entry criteria recruited care general practitioners psychiatrists study participants healthy nonsmoking depressed individuals medication free num months main outcome measure harmine labeled carbon num radioligand selective mao-a positron emission tomography measure mao-a dvs specific distribution volume index mao-a density brain regions prefrontal cortex anterior cingulate cortex posterior cingulate cortex caudate putamen thalamus anterior temporal cortex midbrain hippocampus parahippocampus results mao-a dvs highly significantly elevated brain region assessed test num num num mao-a dvs elevated average num sds brain major depression conclusions sizable magnitude finding absence compelling explanations monoamine loss major depressive episodes led conclusion elevated mao-a density primary monoamine-lowering process major depression
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PLAIN-3474 | MED-3547 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
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PLAIN-3474 | MED-4632 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| effect vegetarian diets plasma lipid platelet levels pubmed ncbi abstract vegetarians apparent diminished risk development ischemic coronary heart disease secondary dietary effects plasma lipids lipoproteins platelets play role observed aberrant functions vegetarians measured plasma lipid lipoprotein levels platelet function platelet fatty acid levels platelet active prostaglandins ten strict vegetarians vegans num lactovegetarians num age sex-matched omnivorous controls striking observations highly significant rise platelet linoleic acid concentration decline platelet arachidonic acid concentration vegetarian subgroups compared omnivorous controls serum thromboxane prostacyclin levels results platelet aggregation studies differ groups tested cholesterol levels significantly lower vegetarian groups compared controls plasma high low-density lipoprotein levels lower vegan subgroup compared omnivores diet produces platelet fatty acid plasma lipid levels contribute decreased risk coronary heart disease possibly atherosclerosis vegetarians
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PLAIN-3474 | MED-4633 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| vegetarian diets healthy mood states cross-sectional study seventh day adventist adults abstract background physical health status vegetarians extensively reported limited research mental health status vegetarians regard mood vegetarian diets exclude fish major dietary source eicosapentaenoic acid epa docosahexaenoic acid dha critical regulators brain cell structure function omnivorous diets low epa dha linked impaired mood states observational experimental studies methods examined associations mood state polyunsaturated fatty acid intake result adherence vegetarian omnivorous diet cross-sectional study num healthy seventh day adventist men women residing southwest participants completed quantitative food frequency questionnaire depression anxiety stress scale dass profile mood states poms questionnaires results vegetarians veg:n num reported significantly negative emotion omnivores omn:n num measured total dass poms scores num num num num num num num num num num veg reported significantly lower intakes epa num dha num omega num fatty acid arachidonic acid aa num reported higher intakes shorter-chain linolenic acid num linoleic acid num omn total dass poms scores positively related intakes epa num dha num aa num inversely related intakes ala num la num indicating participants low intakes epa dha aa high intakes ala la mood conclusions vegetarian diet profile adversely affect mood low intake long-chain omega num fatty acids
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PLAIN-3474 | MED-4634 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| fatty acid profile human saliva indicator dietary fat intake pubmed ncbi abstract objective conventional food questionnaires precise assessing dietary fatty acids purpose study determine relationship salivary fatty acid profile alimentary habits groups attempt develop reliable determine lipidic intake design twenty adults sexes mixed vegetarian diets studied data fat intake obtained means food frequency questionnaire ffq presence main salivary fatty acids determined gas chromatography results greater salivary concentration alpha-linolenic acid num num num found subjects num num whilst arachidonic acid num num lower num num num difference arachidonic acid observed dietary fatty acid intake showing significant correlation dietary salivary levels vegetarian subjects conclusions results show salivary arachidonic acid relevant eicosanoid production related tumourigenesis process cardiovascular diseases influenced dietary fats
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PLAIN-3474 | MED-4370 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
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PLAIN-3474 | MED-3373 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| influence social involvement neighborhood aesthetics community garden participation fruit vegetable consumption abstract objectives considered relationship urban adult population's fruit vegetable consumption selected social psychological processes beneficial aesthetic experiences garden participation methods conducted population-based survey representing num residents num block groups denver colorado num num multilevel statistical models evaluate survey data results neighborhood aesthetics social involvement community garden participation significantly fruit vegetable intake community gardeners consumed fruits vegetables num times day compared home gardeners num times day nongardeners num times day num community gardeners met national recommendations consume fruits vegetables num times day compared num home gardeners num nongardeners conclusions study results shed light neighborhood processes affect food-related behaviors insights potential community gardens affect behaviors qualities intrinsic community gardens make unique intervention narrow divide people places food grown increase local opportunities eat
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PLAIN-3474 | MED-5045 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| suppressive effects selected food phytochemicals cd num expression nci-n num gastric carcinoma cells abstract helicobacter pylori pylori widespread human pathogens plays major roles chronic gastritis gastric cancer cd num gastric epithelial cells recently identified adhesion molecule urease pylori study found cd num highly expressed constitutive manner nci-n num human gastric carcinoma cells protein mrna levels compared hs num t /int fetal gastric cells subsequently cell-based elisa rapidly screen suppressive agents cd num expression established nci-n num cells treated separately num food phytochemicals num num num subjected assay results citrus coumarin bergamottin promising compound lc num ic num greater num luteolin num nobiletin num quercetin num findings suggest cd num suppressants unique candidates preventing pylori adhesion subsequent infection reasonable action mechanisms
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PLAIN-3474 | MED-4094 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| dietary fiber breast cancer risk systematic review meta-analysis prospective studies pubmed ncbi abstract background evidence case-control studies suggest dietary fiber inversely related breast cancer risk unclear supported prospective data conducted systematic review meta-analysis evidence prospective studies methods pubmed searched prospective studies fiber intake breast cancer risk num august num random effects models estimate summary relative risks rrs results sixteen prospective studies included summary rr highest versus lowest intake num num confidence interval ci num num num num dietary fiber num num ci num num num num fruit fiber num num ci num num num num vegetable fiber num num ci num num num num cereal fiber num num ci num num num num soluble fiber num num ci num num num num insoluble fiber summary rr num g/day dietary fiber num num ci num num num num p heterogeneity num stratified analyses inverse association observed studies large range num g/day high level intake num g/day conclusion meta-analysis prospective studies inverse association dietary fiber intake breast cancer risk
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PLAIN-3474 | MED-2853 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| gestational diabetes pregnancy outcomes systematic review world health organization international association diabetes pregnancy study groups iadpsg diagnostic criteria abstract background criteria based num num ogtt diagnosis gestational diabetes gdm recommended years world health organization recently recommended international association diabetes pregnancy study group iadpsg generated hapo study based pregnancy outcomes aim systematically review evidence associations gdm criteria adverse outcomes methods searched relevant studies medline embase lilacs cochrane library cinhal who-afro library imsear emcat imemr wprim included cohort studies permitting evaluation gdm diagnosed iadpsg criteria adverse maternal perinatal outcomes untreated women studies universal application num ogtt included relative risks rrs num confidence intervals ci obtained study combined study results random-effects model inconsistency studies defined inconsistency index num num results data extracted studies totaling num women greater risk adverse outcomes observed diagnostic criteria criteria consistent associations macrosomia rr num num ci num num num large gestational age rr num num ci num num num perinatal mortality rr num num ci num num num preeclampsia rr num num ci num num num cesarean delivery rr num num ci num num num data iadpsg criteria associations inconsistent studies num num magnitudes rrs num cis num num num num large gestational age num num num num preeclampsia num num num num cesarean delivery excluding hapo ebdg studies minimally altered associations rrs iadpsg criteria reduced excluding hapo conclusions iadpsg criteria gdm identified women small increased risk adverse pregnancy outcomes associations similar magnitude criteria high inconsistency iadpsg criteria full evaluation settings hapo requires additional studies
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PLAIN-3474 | MED-1745 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| chemical composition glyphosate-tolerant soybean num num grown europe remains equivalent conventional soybean glycine max pubmed ncbi abstract composition glyphosate-tolerant roundup ready soybean num num compared conventional soybean grown romania num part comparative safety assessment program samples collected replicated field trials compositional analyses performed measure proximates moisture fat ash protein carbohydrates calculation fiber amino acids fatty acids isoflavones raffinose stachyose phytic acid trypsin inhibitor lectin grain proximates fiber forage values biochemical components assessed roundup ready soybean num num similar conventional control published range observed commercial soybean compositional profile roundup ready soybean num num compared conventional soybean varieties grown romania calculating num tolerance interval describe compositional variability population traditional soybean varieties marketplace comparisons history safe soybean common component animal feed human food lead conclusion roundup ready soybean num num compositionally equivalent safe nutritious conventional soybean varieties grown commercially
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PLAIN-3474 | MED-4687 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
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PLAIN-3474 | MED-2035 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| gluten-sensitive diarrhea evidence celiac disease pubmed ncbi abstract adult female patients suffering abdominal pain chronic diarrhea incapacitating frequently nocturnal dramatic relief gluten-free diet return symptoms gluten challenge previous nonspecific measures milk-free diet ineffective multiple jejunal biopsies showed minor significant cellularity returned normal gluten-free diet slight increase jejunal cellularity immunological abnormalities found gluten challenge steatorrhea biochemical defects common celiac disease found concluded patients gluten-sensitive diarrhea evidence celiac disease
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PLAIN-3474 | MED-3320 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| industrial hygiene assessment reticuloendotheliosis viruses exposure poultry industry pubmed ncbi abstract objectives reticuloendotheliosis viruses rev group retroviruses avian leukosis/sarcoma viruses alsv naturally infect cancers chickens recently found alsv antibody levels job tasks poultry industry objectives study examine similar association found rev antibody levels examine correlation rev alsv antibody levels methods relative risk estimated comparing rev antibody levels num poultry workers num controls expected antibody level predicted association employment generalized linear model correlation coefficient measured alsv rev antibody levels results rev antibody levels significantly higher poultry workers control subjects gender employment conditions employment duration relative risk significantly higher job categories significant correlation observed rev alsv antibody levels strong poultry workers weak control subjects conclusion antibody levels validly identify job tasks high risk exposure rev workplace practical implication recommendations protection job tasks importantly situations exposure multiple pathogens workplace analysis antibody levels pathogen sufficiently represent exposure correlated pathogens suggested exposure assessment hold true pathogens similar route transmission
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PLAIN-3474 | MED-5144 | fish consumption and suicide depression is a serious and common mental disorder responsible for the majority of suicides , but as i already covered , intake of fruits , vegetables , and naturally occurring antioxidants have been found to be protectively associated with depression . so , they concluded , it may be possible to prevent depression or to lessen its negative effects through dietary intervention.but not so fast . this was a cross-sectional study , meaning a snapshot in time ; so , you don โ t know whether the poor dietary pattern precedes the development of depression or if depression causes poor dietary intake . depression and even treatments for depression can affect appetite and dietary intake . maybe people who feel crappier , just eat crappier , instead of the other way around . what you need is a prospective study , a study performed over time , where you start out with people who are not depressed and follow them for 6 years , and those with higher carotenoid levels in their bloodstream , which is considered a good indicator of fruit and vegetable intake , had a 28 % lower risk of becoming depressed within that time . so , the researchers conclude that having low blood levels of those healthy phytonutrients may predict the development of new depressive symptoms , but what about suicide ? worldwide , a million people kill themselves every year . in this comparison of european countries , greece had the lowest rates of suicide . maybe it โ s the balmy weather , but maybe it has something to do with their diet . 10,000 people followed for years , and those following a more mediterranean diet pattern were less likely to be diagnosed with depression . what was it about the diet that was protective ? it wasn โ t the red wine , or fish ; it was the fruit and nuts and effectively higher plant to animal fat ratio and beans that appeared protective . conversely , significant adverse trends were observed for dairy and meat consumption.a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders.one possible explanation could be the mercury content of fish . an accumulation of mercury compounds could increase the risk of depression . we know that mercury in fish can cause neurological damage , such as negative effects on alzheimer disease , memory loss , and autism as well as depression.so , the increased risk of suicide among persons with a high fish intake might be attributable to the harmful effects of mercury in fish.the big harvard cohorts found similar results ; hundreds of thousands followed for up to 20 years , and no evidence that taking fish oil or eating fish lowered risk of suicide , with a trend towards even higher suicide mortality.what about for the treatment of depression ? neither epa nor dha appeared more effective than sugar pills , and the same can be said when one puts all the trials done to date together . we used to think omega-3 supplementation was useful , but several recent studies have tipped the balance the other way . it seems that nearly all of the treatment efficacy observed in the published literature may be attributable to publication bias , meaning the trials that showed no benefit tended not to get published at all , and so all one saw was a bunch of positive studies , but only because a bunch of the negative ones were buried. apart from the amathing wfpd would you recommend to take vegan dha for a old woman that have memory loss and depression ? ( we are giving her ? ) im considering to buy dha but can affect that negatively ? hi noe . it โ s a great question . here are dr. greger โ s optimal nutrition recommendations and all of the information we have on dha . you might consider taking dha if your doctor is pushing it , and you feel intake of other fats ( flax , walnuts ) are not adequate . elongating ala to epa / dha is controversial . some folks who are following a vegan diet just take it as precaution whether they really need it or not . i see nothing wrong with this approach so long as it ; s not causing more harm . i don โ t think it will negatively impact mood , but it may cause the blood to thin more than normal . if that happens check with your doctor about lowering dosage or discontinuing.thank you ! thank you joseph gonzales.does mercury from the amalgam in teeth be a source of mercury in blood ? if one have one old amalgam how have to take it out get badly contaminated with that ? or the quantities of that is small compare to fish consumption ? not a huge concern.http : / / www.fda.gov / medicaldevices / productsandmedicalprocedures / dentalproducts / dentalamalgam / ucm171094.htmmacsmiley : the document you โ ve cited is from fda . personally , i don โ t believe anything fda says.sorry , but your anti-establimentarianism is not my concern . i โ m on a cellphone and do not have full access to research.how about stephen barrett ? http : / / www.quackwatch.com / 01quackeryrelatedtopics / mercury.htmlwell i don โ t have any anti establishment idea behind .. and just for objective reason , you can see the effect of glifosato in argentina. the rise in allergies , cancer , etc .. fda approved that .. what to say .. i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand https : / / www.youtube.com / watch ? v = n6 _ dbvdvo-k โ i don โ t like conspiracys documentarys but i think this is not one of thouse , you can hear from first hand โ heh and yet you reference โ documentary โ sponsored by gmo-free companies they of course dont have conflict of interest โฆ .you need to do more research on stephen barrett . after doing so i do not believe that you will take anything he says seriously.the same we can say about author of this site , barrett spead many misinformation but about here he have right . he also have many good articles ( not all of course ) sorry but after see whats fda says on monsanto products like glifosato .. i can not trust in fda , it seems drive by different lobbies it self โฆ the problem is not glyphosate , but roundup ยฎ , which isn โ t just glyphosate . the only long term toxicology study to use commercially formulation of roundup ยฎ โ and not glyphosate alone โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying . can you guess why ? nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . however , that doesn โ t mean everything the fda says is wrong . when things cannot be denied anymore it goes in public warning labels , but the drugs industry are just going for the news drugs anyway .. โ . can you guess why ? โ you knoe that this study was retracted due to methodological error . โ is seralini โ s study , which have been withdrawn from the scientific literature thanks to monsanto lobbying โ if you check facts you will be see why this study was retracted even freshman will know that by the same you can show that everything is bad for us , what is more funny this study was also heavly lobbed by gmo-free companies . โ nothing should stop the progression of the american empire and the greed of the big corporation on which it โ s based upon . the fda in this picture is just a prostitute to serve the biggest interest , that is not the public of course . โ maybe check again gmo free companies made more money than monsato , spend more on marketing etc.the thing you should have guessed is because it show adverse effect . and no the study does not have methodological error . they use the exact same strain of rats and methodology than the study used by monsanto to put gmo on the market . so if this study had to be withdrawn , the monsanto โ s study too . but it โ s not , of course , they need to control the world by controlling the seed and they have lot of money to spend on discrediting idea on the web , indeed mister guest.look at both sides of the issue . mercury in the mouth is poison . the stuff is handled with extreme caution until it is put in your mouth , them all of a sudden it is harmless ? ? ? i have a very hard time with that . โ i have a very hard time with that . โ and i have hard with people without basic knowledge in topic in which they wrote , first rule of toxicology : the dose make poison . water also can kill you in proper dose.i would go to see my dentist in the next days and tell him , please remove the amalgan now . but please use all the seafty precautions . if it removed than , i would take some fiber in addition like indian fleaseed husk for the next month . if you already a plant based eater i would think its enough , if not , than it is the best time to start it . ; - ) it was plausibly argued the last time i looked into this concern , that the exposure to mercury whilst having fillings removed would far exceed the risks of leaving them in your teeth . and i used to eat a lot of tuna and salmon โฆ nevermore.that โ s only the half true , sorry . the informed dentists in germany remove all the amalgan of there patients because the mercury is only ( maybe ) save if the fillings are not micro demaged . you are right , there is a big risk by removing them . but informed dentist knows how to do , how to protect the patient and ( ! ) the dentist by himself . i just joined a seminar about this theme โฆ interestingly dr. greger has a video about amalgam fillings and canned tuna . it may help.i have to say that i don โ t agree with the conclusion sugent in that video. in nutrition facts michael says , it is not a good thing compare something with the worth things .. if fish is worst doesn โ t mean amalgam is safe ! ( it is not said but sugest in the video link ) the other day an amalgam have break to my aunt during night , she have swallowed part of it without notices. amalgam breaks .. and its relatively common .. so what about the amount of mercury when you eat that , or more offen even , the dentist repair againg the old ones to make new ones with no any protection , you actually swallow a lot of amalgam there .. there is any study on that ? i don โ t think he is saying amalgam fillings are safe , but that mercury from one can of tuna a week is like having 29 fillings . both ought to be avoided ( or heavily reduced ) to prevent mercury from accumulating.it will be great to put some light on the amalgam fillings topic. and mercury en vaccination , a friend of my have start multiple sclerosis after a particular vaccination that have contain mercury in it โฆ even the hospital have assumed that. after 10 years she still with ms. and it was consider a safe amount .. it may be a rare case. but the vaccination topic awake a huge debate as well.i personally don โ t know the answer but i would say yes absolutely . i went and had mercury fillings removed . i now have more energy and less digestion issues which were quite sever before i had them removed . not 100 better but like 80 percent better after removing.if you can afford it you can have your fillings removed safely by an iaomt dentist . once all mercury is out the safest way to chelate is with frequent dose chelation . mercury is one of the most toxic substances and putting it in your mouth ( or vaccine ) is just stupid.thank you for the great resource . i recently wrote up an article about the fishiness behind the science of fish : http : / / www.carobcherub.com / fish-healthy-science / i โ ll have to look more into this caveat of information and add it . while most health boards recommend fish consumption , the risks just don โ t seem to outweigh the potential benefits , especially when those benefits can be more safely obtained elsewhere.and finally a topic of healthy eating has reached the medical community โ recommending higher intake of fish for various ailments , brainhealth ( incl depression ) , cardiovascular disease and so on โ and then it turns out that it is wrong ! of course the followers of this site has known for years that fish is not a health food.a poster below posted this comment . i ask you , as you are a doctor and knowledgeable of this matter today , but this person seems to have made a very valid point that was not portrayed today and likely should have , if the truth is what we are after here . what are your thoughts , as the few servings of fish per week was found to be protective . the integrity of our vegan community depends on clarity on this sort of stuff . โ that last line is also in agreement with the japanese paper you ( dr. greger ) cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why . โ more fear-mongering on fish . dr greger please stick to the good proactive stuff on what we should eat rather than cherry-pick on this anti-fish agenda โ as this poster says โ it demeans your message to the point where your credibility is lessened . i just read the blue zones โ and none of those longevity cultures were vegan . in fact โ i ask anyone to point to any historical longevity culture that was strictly vegan . meat was infrequent , yes โ and no one ate beef , but they had the occasional eggs , goat milk , fish , chicken , and pork and thrived.dr. greger has said that those who ate meat โ on occasion โ โ outlived them all . โ he has also shown that among many regions in other countries that can โ t afford meat our chronic diseases are absent . however , these people do not outlive us . those who embrace a vegan lifestyle to add life to their years and years to their life do so knowing now it has health benefits . if you read about the blue zones you must be interested in long life . some people have other strategies , including the use of supplements , like tor . being vegan is a recent invention and so we don โ t know how much it could add . there are other ways to avoid chronic illness . the people in the blue zones eat meat once a month at most , and the longest lived among them were the lora dunning adventist vegetarians . they still only lived 4-7 years longer , and this is a similar benefit to going to going to church or being in a tight nit social community , though without doubt their abstinence adds to their lives . do you think eating fish is necessary to add to life ? i think you probably already are on a โ calorie restricted โ diet for long life and that โ s what everyone here wants . i think that dr. greger has research that regular fish consumption is not a health related life style . he also doesn โ t recommend any alcohol , but almost all blue zone members drank lightly . what blue zone attitudes do you want to take for a long life ? i don โ t think anyone can point to a vegan culture , the term being made in the 1940s.on average , the traditional okinawan diet provided 1 % of calories from fish and less than 1 % of calories from beef , poultry , and dairy.http : / / www.okicent.org / docs / anyas _ cr _ diet _ 2007 _ 1114 _ 434s.pdfyou can say they weren โ t vegan , and technically this is correct , but if the health benefits of a vegan versus non-vegan diet has been reduced to that which makes up 1 % of calories in a diet , then the debate is over.the adventist โ s that live the longest are the vegan adventists . check out the documentary โ ancient health โ at anchorpointfilms.com. it talks about this.the blue zones study showed that what those areas had in common for diet was a mostly plant-based diet with beans a being very important part of the diet as well as fresh fruit and veggies and grains . i am a fan of the blue zones . here is a short video they posted recently that sums it up : https : / / www.facebook.com / bluezones / videos / 10153216071989270 / ? pnref = storythe people in the blue zones ate very little of the animal foods you mention . i believe it was about 5 % or less of their diet . usually once or twice a month.the article above says this โ a similar protective dietary pattern was found in japan ; a high intake of vegetables , fruit , mushrooms and soy products was associated with a decreased prevalence of depressive symptoms . it was not characterized by a high intake of seafood . 100,000 japanese men and women were followed for up to 10 years , and they didn โ t find evidence of a protective role of higher fish consumption or the long chain omega 3 โ s epa and dha against suicide . in fact , they found a significantly increased risk of suicide among male nondrinkers with high seafood omega 3 intake . this may have just been by chance , but a similar result was found in the mediterranean . high baseline fish consumption together with an increase in consumption were associated with an increased risk of mental disorders . โ it says that those with a high seafood omega 3 intake had a significantly increased rate of suicide.on what grounds then does the good doctor recommend algae dha ? so if the rda for โ fat โ is 60 grams a day , and this site has as a side component a very low fat diet ( whole foods , plant based ) , then they are recommending some plant based sources of fat like walnuts and flax seeds . the rda for fat is not broken down into omega 3 versus omega 6 and omega 3 is not broken down any further . someone thinks you need at least 60 grams a day but users of this site probably get far less . could you get 60 grams of fat a day from nuts and a whole foods plant based diet ? is there such a thing as a fat deficiency ? clearly users of this site would agree that meat eaters can get a fat imbalance . there is a rda for saturated fat too , and nuts can fill that but many people here probably on some days get none at all . tropical fats , filled with omega 6s , even plant based , may not be good for people in the temperate zone . he says in the video plant based fats are good for mood , but this site does not recommend added oils like olive oils , in part because of the great wealth that is lost from it in processing ( let โ s try to get cloudy olive oil ) . one fifth of america suffers from mental illness each year . ala from flax seeds might improve mood in many of these people , or at least , that is what i have been told . the traditional fish oil might lead to mercury related depression . perhaps beans could also improve mood . so , i would also like to ask , do you feel plant based omega three oils are good for mood ? i understand that they are not a โ whole food . โ would you advice against a one for one replacement of fish oil with flax seed oil for mood ? mathew smith : re : โ is there such a thing as a fat deficiency ? โ in a talk from dr. mcdouggall some time ago , i believe i heard him say that there is a name / condition for a person who does not get enough fat , but that such a condition is a theory , not something you see in practice in the real world โ at least not in america where people get enough calories.i don โ t know if this is true or not . just thought i would pass it on as an interesting thought.thank you . of course a low fat diet is preferable . i have been budgeting most of my calories to nuts . dr. greger has a video in which he says cholesterol has a tolerable threshold of zero . what a great ideal , realized here by vegans. http : / / nutritionfacts.org / video / trans-fat-saturated-fat-and-cholesterol-tolerable-upper-intake-of-zero / your premise is false for the usda at least . there is no rda for fat for non-infants : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / dri _ rdas _ adequate _ intakes _ total _ water _ macronutrients.pdfthey do have tables of amdrs dating from the 2002-05 , report which are nowhere near 60g / d even at the upper end : http : / / www.nal.usda.gov / fnic / dri / dri _ tables / macronutrients.pdfnote that the concerns that they express for values below the amdr are entirely based on cardiovascular biomarkers : tc and hdl.thank you , i was referring to what is on the nutrition label . the nal has omega 6 to 3 ratios that are way out of balance . with recommended values that low , i โ m surprised so many are ala deficient.the ratios are way out of balance because they take ai for ala and la to just be the median intake of the us , and the us is basically a population with ratios that are out of balance . here i assume that you mean โ balance โ to be a dietary n6-n3 ratio ranging from 1 or so to an upper limit of 4.from where are you sourcing the idea that many people are actually ala-deficient , as opposed to simply being out of balance ? please see this link. http : / / www.enotes.com / topics / omega-3-phenomenoni do not have the book โ the omega 3 phenomenon โ but rudin was a big advocate for omega 3s for serious mental illness.in all likelihood he wasn โ t judging people to be ala deficient in relation to the rda . are you surprised because you think otherwise , that his judgment is correct , and that therefore many people have ala intakes far below the rda ? yes . thank you . i am very surprised.but it looks like he typically recommended amounts like 2 tablespoons of flaxseed oil a day , with half a teaspoon as the absolute lower limit : https : / / books.google.com / books ? id = fomlb2ksak0c & q = flax + oil # v = snippet & q = daily & f = false ( p . 139 ) at 7g ala per tbsp , that โ s an absolute minimum of 2.3g on top of whatever is in the rest of the diet . that โ s well in excess of the usda ai for ala . at 2 tablespoons or more for many people following his program , that โ s far in excess of median intake . it seems that his standards of inadequate intake had nothing to do with the ai.thank you . if i were to critically assess my statement , i would say the book authors would argue the rda for ala is too low , with my comment about the recommended fat allotment not being pertinent or not segregating out enough information . he notes mood improvement with less agitation with flax seed oil supplementation . do you feel this is only due to placebo effect , or would say even finer essential fatty acid supplementation might improve mood as well ? thea has alluded that dr. greger would like to change his dietary recommendations . for those of us who are not lifelong vegans deficiencies abound and lead to chronic illness . thank you for researching this . you are accurate and i would have to step back and say , i agree with you . i am surprised fat is recommended at all and low fat diets are healthy . i am probably eating more healthy fats since joining this site . i actually felt better when i was on a non fat diet . i should step back , and give thanks to you instead because i raised my hdl and lowered my triglycerides with niacin . if it weren โ t for that , maybe they were bad because i was eating too much fat . i would like to agree with you and apologize that my point was not relevant . there are many diets coming together here besides whole food plant based , including low fat and vegan . is that dr. greger โ s purpose ? thea has also said he is preparing meal plans . maybe we can gain insight on that from those in december , which i โ m very impatient for.i have no deep idea of rudin โ s argument but i see no particular reason to trust him . he was a psychiatrist who doubled down on a single nutrient as the key to general health , as far as i can tell . i don โ t really trust that line of argumentation , nor do i lend him all that much authority to comment on nutrition as an expert , and i โ m especially unwilling to give him the kind of expertise needed to demonstrate an a wide-ranging importance of one specific nutrient . as far as i can see published no academic research on n-3 , and presented no systematic study on his โ omega plan โ the popular press , like the web , is filled with miracle diet plans , and i see little reason to investigate them all.that said , i โ m open to the possibility of this or that effect from ala supplementation . i would just prefer to get that information from proper sources . i โ m not really familiar with the primary literature that might relate ala supplementation with improved mood above and beyond placebo . depending on its extent , getting familiar may take time.i identify nf as basically a wfpb site . yes , there are vegan and low-fat viewpoints present here but it โ s because they are interested in vegan and low-fat diets in combination with the wfpb idea . there โ s some convergence on a preference for lower fat in the wfpb world but this preference isn โ t uniform . i don โ t think that very high fat plant based diets are nearly as common . it will be interesting if greger comes out with meal plans but i won โ t necessarily follow his plan myself . i treat nf more as a news source than an authoritative body of recommendations as it is . i value other opinions . greger may become more important as a popular leader in the wfpb world as time goes on and older figureheads age and die , and i certainly admit that it will be interesting to see how nf develops over time.there are certain elements of nutritional research that i don โ t follow very diligently due to lack of personal investment . it โ s not that i โ m trying to overcome any specific ailment , but rather that i โ m trying to take a primordial preventative approach to the major killers , focusing less on specific foods and more on the general ideas that have the strongest support . i haven โ t seen much to recommend high-dose niacin supplementation as part of my long-term strategy in the first place , but from what i recall seeing i โ m suspicious of the idea that niacin has therapeutic use in reducing cardiovascular risk . part of this stems from my doubts about hdl as a broadly robust biomarker in mechanistic and statistical terms ( my more direct concern ) , and part from relatively disappointing results of niacin in actual trials in particular ( e.g , http : / / www.bmj.com / content / 349 / bmj.g4379.long ) . you may want to investigate the topic area and see what โ s credible , since the idea that โ functional โ hdl is the more appropriate target seems to be getting a lot of discussion among researchers of late.thank you very much for your comment . niacin worked for me . a study in those with heart attacks , those on niacin lived two years longer than expected . i am curious to see how long it will work for me , and what benefit to lifespan high niacin will have for me if i do it for as long as i need it . big drug interests are hoping to make a more profitable drug . there are some vitamins that improve longevity . these include niacin , parthenoic acid , melatonin , vitamin d , astaxanthin , coq10 , vitamin k2 , magnesium , egcg , folate , vitamin b12 , curcumin , and vitamin a , selenium has great anti-cancer properties . i found after high vitamin d therapy that i am shockingly deficient in this nutrient . i am also fearful that i am shockingly deficient in many other nutrients but am below the clinical diagnosis level . i was shockingly deficient in iodine . it is great to take an iodine supplement now , i don โ t feel my heartbeat now and must be calmer for that effect . before my heartbeat was steadily getting louder , i guess . my back pain and ankle went away on iodine ( had tendonitis , gone with iodine ) . i really want to find out what i am still deficient in to improve health . this site has vitamin recommendations . when i read that they are only true for white people due to research bias , my first reaction was that minorities have less deficiencies . with vitamin d alone they probably have more . this site does not recommend supplements , preferring the whole plant . i think this is great logic . as nature intended . imagine the drugs that are present in say an apple that we can โ t get at because they are too small or diffuse . so i admit i cheat when i use supplements . i am using the concept of concentration . i am missing out by not eating the whole thing . this shortcut taken to its logical extreme is sickening america . however , i am very interesting in medicine and the location of iodine as the treatment for goiter was the basis for modern medicine ( before it was known that sea sponge could cure goiter ) . this process is medicine and i think if taken sanely can still save modern medicine . what was after iodine ? vitamin c for scurvy ? maybe niacin for pellagra / schizophrenia would be part 2 that hasn โ t happened yet . dr. greger would love to show us that modern non-whole food processes are robbing us of nutrients and is sickening us . maybe high blood pressure is a sulfur deficiency exacerbated by freshening vegetables . . could you imagine ? there is at least a small amount of backlash against the aim-high and hps2-thrive studies.alex : good question.note : dr. greger โ s current nutrition recommendations go back to a post that is dated 2011 . he has hinted along the way that he wants to update those recommendations , but he hasn โ t done so to date . recently , we learned that dr. greger โ s new book that is coming out in december will have meal plans . i assume that means that the book will also have updated nutrition recommendations . so , hopefully we will find out in december if dr. greger still recommends dha supplementation or not and if so , why . the answer would presumably be based on the body of evidence , ie , a whole bunch of studies and all the studies together , rather than a single study.that โ s my guess on the answer to your question . sort of an answer anyway.fish oil pills are being prescribed now to lower triglycerides . niacin in large doses can cut them by half ( the same niacin robbed from grain in the mills ) . i would ask if these pills , not for mood for triglycerides , can cause depression or other mercury related problems . .quick question . regarding dha supplementation mentioned at the end . does that mean there is a chance that dha supplements are not protective and that dietary intake of omega 6 and omega 3 in the ideal ratio is really the only protective method ? so at least in premise you โ d agree that modern americans have a deficiency of essential fatty acids , and supplementation could be therapeutic . the video seems contradictory in saying โ effectively higher plant to animal fat ratio โ but not epa / dha are health promoting . i would be thrilled if we have addressed the essential fatty acid deficiency.this video seems very dishonest when looking at the sources you gave . from the mediterranean diet paper ( sun cohort ) : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) โ โ the hrs ( 95 % cis ) were 0.67 ( 0.54-0.84 ) for fruit and nuts , 0.71 ( 0.57-0.88 ) for legumes , 0.73 ( 0.59-0.91 ) for fish , and 0.79 ( 0.63-1.00 ) for the mufa : sfa ratio . โ โ the sun cohort , in another analysis , found that moderate to high levels of fish consumption ( third through fourth quintiles ) exhibited a relative risk reduction of mental disorders greater than 30 % . โ โ our results are consistent with the possibility that very low fish consumption is associated with an increased risk of depression , but once a threshold of intake is reached , no further reduction in risk is obtained . โ that last line is also in agreement with the japanese paper you cited : โ a significantly increased risk of suicidal death was observed among women with very low intake of fish , with hrs ( 95 % ci ) for those in 0-5th percentile versus middle quintile of 3.41 ( 1.36-8.51 ) . โ so the papers you chose to use are actually arguing for a few servings of fish a week as protective , rather than strict avoidance or daily consumption . normally i agree with your videos , but this one was very badly done and just hurts the image of the website . when people accuse dr. greger of cherrypicking , this is why.the sun cohort results are open to two different interpretations . dr greger โ s interpretation that fish consumption was not protective against depression is perfectly legitimate if you have a look at table 3 , where there is no significant linear trend for fish ( while there is a significant protective effect of fruit / nuts , legumes , mufa / sfa ratio ) . i note that you have left this bit off your first quoted sentence , which , to quote the complete sentence is : โ with regard to fish intake , a reduction in risk of more than 20 % was observed for intermediate quintiles ( third and fourth ) , although the linear trend was not significant โ . on the other hand , when they combined the upper three quintiles of consumption and compared it with the lowest , a significant protective association for fish emerged . so yes , with a little data massaging there is a suggestion of a protective effect of fish . but if you want to go by the planned analysis ( shown in table 3 ) , which finds no signficant linear trend for fish , then dr greger โ s interpretation is quite correct . the fact that the researchers themselves did not mention fish in the abstract suggests that they too concur with dr greger โ s interpretation.there wasn โ t a linear trend for fish , but like that study and the japanese study suggest , this may be due to there being a theshold beyond which fish consumption may lose some benefit , possibly because the influence of the heavy metals begins to outweigh the omega-3s.in both studies , fish consumption in general was considered protective , and in the japanese study there was more than a three-fold risk of suicide in women who ate little or no fish compared to the middle quintiles of fish consumption . if dr. greger has the data to investigate that further or to provide evidence that another omega-3 source may work better than fish , that would be a good thing to make a video on . in this video though , he seemed to try to make his referenced papers look like they say the opposite of what they actually say by withholding information . it โ d be much better to show exactly what the study found and then explain why it might be so.the paper showing that epa and dha supplementation in a randomized , double-blind , placebo-controlled trial didn โ t improve mental health makes me wonder though if the mood-related benefits shown for moderate fish consumption might actually be due to another nutrient , like vitamin d , which fish have relatively high amounts of as well . i โ d like to see a study adjust their data for vitamin d status and see if fish consumption is still independently protective at any level . for people who would otherwise have low blood levels of vitamin d from staying out of the sun , the vitamin d taken in from food could give a significant benefit . with fish being really the only significant food source of vitamin d , it โ d make sense that fish consumption would appear protective in populations where suboptimal vitamin d levels are common.add to the above that fukushima โ s ongoing โข pollution of the pacific ocean and you get a perfect storm of negative benefits from eating โ tainted โ food whether it is fish or plants . covered fish farms and / or greenhouses will become the norm as ever more environmental pollution makes traditional outdoor gardening hazardous to your health.please , can anyone held a german by explaining the meaning of epa and dha ? thank you so much โฆ ; - ) epa โ ( environmental protection agency ) establishes guidelines that must be followed , but lately they are being โ gutted โ by our congress , in order to help these big corp. โ s ( who donate big $ $ $ ) have to provide less safeguards and therefore make more profits.thank you , you saved my night sleep today . : - ) ) steffen โ happy to help ! btw : germany is my hero since they are modeling the way toward residential solar energy freedom ( once the loan is repaid ) and phasing out their nuclear and coal energy generation at the same time ! in the usa , both the nrc and the epa are being muzzled by congress since the majority of congress are now caving into industry demands for ever less oversight in order to protect their large donors.as many of us know , removing regulations , will only make the next accident occur sooner ! here is a great example : gop guts epa http : / / www.huff.to / 1chhqcjthey are modeling the way toward residential solar energy freedomreally ? sounds great but i didn โ t think germany was bright enough for solar โฆ do you have a link ? jeewanu โ http : / / washingtonspectator.org / nuclear-age-began-70-years-ago / # comment-9858hi steffen . eicosapentaenoic acid ( epa ) and docosahexaenoic acid ( dha ) are essential omega 3 fatty acids . they are found in fish oil and algae omega 3 supplements. http : / / nutritionfacts.org / topics / fish-oil / thank you julie , that makes more sence for me โฆ because i already heart a little bit about epa and dhaby professor dr. walther veith from south afrika university.the omega 3s found in walnuts , flax seeds , and algal derived sources are purer than found in fish ? if only fish oil had the mercury removed . omega 3 is a large component of the structure of the brain and other parts of the body . you could flip this very study and suggest that foods rich in omega 3s without mercury , like nuts , have been found to be good for mood . fish is not a health food , but maybe the algae they eat to get to make their omega 3s ( epa , dha ) are a health food . omega 3s make up much of the structure of some parts of the body , including the brain , and are important for regrowth . what is the turn over for our omega 3s in this sense ? how much ala do we really need ? is there a recommendation on walnuts and flax seeds ? it was an โ effectively higher plant to animal fat ratio and beans that appeared protective โ against suicide . oh thank goodness ! a recommendation to eat more plants for mood.my understanding is that organochlorines such as pcbs are stored in fat , while mercury is stored in lean tissue of fish.http : / / www.nutraingredients-usa.com / research / omega-3-ala-intakes-enough-for-epa-dpa-levels-for-non-fish-eatershttp : / / ajcn.nutrition.org / content / 92 / 5 / 1040.full dietary intake and status of n โ 3 polyunsaturated fatty acids in a population of fish-eating and non-fish-eating meat-eaters , vegetarians , and vegans and the precursor-product ratio of ฮฑ-linolenic acid to long-chain n โ 3 polyunsaturated fatty acids : results from the epic-norfolk cohort โ in conclusion , this study found substantial differences in status and detailed intakes of n โ 3 pufas and their sources in different dietary-habit groups in a general population of middle- and older-aged men and women . the precursor-product ratio of ala to circulating n โ 3 pufas was significantly greater in women than in men and in non-fish-eaters than in fish-eaters , which indicated a potentially greater estimated conversion . there were smaller differences than expected in status between fish-eaters and non-fish-eaters , which may also be explained by the greater estimated conversion of ala to lc n โ 3 pufas in the non-fish-eaters . the implications of this study are that , if conversion of plant-based sources of n โ 3 pufas were found to occur in intervention studies , and were sufficient to maintain health , it could have significant consequences for public health recommendations and for preservation of the wild fish supply . โ sorry to everyone for making things more confusing โฆ you might also check out krill oil which is used as a health supplement ! and lol , please tell me what medical study determines โ depression ? โ please push your thumb into your forehead ? r u depressed ? ? r u # hitler ? please research the bogusness of โ mental disorders โ .. they are voted into existence , http : / / www.cchr.com please invest in big pharma if you are pushing a connection between โ depression โ and suicide . i was bigtime into promoting you .. i totally missed any of the bs about โ mental bs โ by you ! muck ! ! ! โฆ and i followed you for years ! ! i should have searched deeper ! with all due respect โฆ .you , as a doctor โฆ .. how many years of studies have you had in the history of psychology / psychiatry ? smmmma ! i will not be promoting โ plantpure nation โ anymore โฆ as i totally promoted you , day in and day out for years ! thank you for showing your belief of the word โ depression . โ i didn โ t understand โ thw word depression โ until i experienced it . it โ s not make believe . i sincerely hope that those close to you are able to get help if they ever need to and not be scoffed at and ridiculed . believe anything you want , but be aware how it make hurt those you love.sorry you feel that way , julie . i am not entirely sure i understand your frustration . as usual all citations and links to more videos can be found throughout this page.what ? ? ? r u hitler ? ? ? seriously , if you have no concept of what depression or mental illness is , consider yourself very fortunate , but do not ridicule the idea of it if you have no experience with it personally ! ! ! i am currently in a very great state mentally , but had battled severe depression all my life โฆ well before i even knew what the heck it was โฆ i just thought that was the way life worked ! not having the desire or ability to get out of bed in the morning to face another horrible day and wanting to not live is not a choice or something you learn ! mental illness has been a plague of ours for eternity and is not a new phenomenon ! i agree that it is more common now and horribly over-prescribed with the medications that abound , and i think this is simply because our natural lives are so out of whack โฆ but true depression and mental illness are as physical and real as any other human disease and have been around as long ! personally speaking , diet and lifestyle changes have been an immense help . though no one has a shortage of โ prozac โ or whatever drug , they did help me get back on track , but are certainly not for everyone as they are being used , therefore there needs to be a way to tell the difference ! ! ! but the inability to experience joy or lack of desire to be alive is not a choice one learns , it descends on you like the plague and sucks away your life . mental disorders are voted into existence ? really ? i โ m wondering if you got a vote ? now also available in portuguese / legendado e publicado em portuguรชs : http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / according to dr. joel furhman , md , dha supplementation is necessary to vegans . do you disagree with that ? i do not necessarily disagree , but the word โ necessary โ is very strong considering there is no dietary requirement for dha or epa , only for essential fatty acids like ala and la . having said that there is reason to believe those following a vegan may benefit from taking dha . here are dr. greger โ s optimal nutrition recommendations . for more in-depth analysis on essential fats check out dietitian jack โ s blog . let me know if this helps . thanks for your post , joy.what supplements do you currently take , and / or are you considering taking ? and do you eat any grains that have been fortified , as in most breads at sandwich shops and even whole foods is now using fortified-organic grains in a lot of their packaged products and salad bars , deli-bars , takeout , etc.thanks. ( nothing to do with this video , new videos have more comments activity , thats all ) hi ! i โ m vegan ( 3,5 years ) and still struggling with acne . i watched your videos on acne and looks like igf-1 triggers mtorc1 signaling that produce acne ( http : / / nutritionfacts.org / video / saving-lives-by-treating-acne-with-diet / ) . since im already vegan ( low fat whole plant based ) i started to do more research on my own . in this video dr. greger says that leucine activates more mtorc1 than other amino acids and animal products have the most dietary amounts of this partirular amino acid ( http : / / nutritionfacts.org / video / caloric-restriction-vs-animal-protein-restriction / ) . could it be that i need to bring leucine intake even lower , for example , reducing beans that , in the plant kindom , are the ones with the highest levels of leucine ? and increase ursolic acid from fruits and spices ? ursolic acid inhibits leucine-stimulated mtor activation ( http : / / www.ncbi.nlm.nih.gov / pmc / articles / pmc3989317 / ) , found in apples , basil , bilberries , cranberries , elder flower , peppermint , rosemary , lavender , oregano , thyme , hawthorn , and prunes . could this be the solution for plant eaters that still suffer acne problems ? thank you for responging ! google โ scd diet โ , but try to do a vegan version of this diet . it works wonders for people , it did for me . follow it exactly , no cheating , avoid all grains and soy , and only eat the beans allowed . you โ ll see a food list of scd legal and scd illegal foods . and don โ t eat anything fried in oil . eat fruit alone , hours away from fat , protein , and other foods . keep it simple , but trust me , scd diet , a vegan version of it , has changed lives . i also avoid fermented foods , for now at least . seems to help , the avoidance.fish is still seen as a healthy food in portugal , at least in the predominant culture . this vรฏdeo will be a great way to start changing that. http : / / nf.focoempatico.net / consumo-de-peixe-e-suicidio / cool ! thanks for an interesting post and thank you , dr. greger , for clarifying the sources of omega 3s in your discussion . whenever i hear about the pros and cons of โ supplementing with omega 3 โณ and the speaker or writer doesn โ t define the source or form of omega 3 ( very common ) i feel troubled because this vague phrase , at least in my mind , can mean consuming fish oil , or algae oil , or eating some ground flax or chia seeds and allowing the parent ala to make epa and dha inside our own bodies . i first learned about the importance of essential fatty acids in the context of eating ground flax and chia , so i never learned to assume that โ supplementing with omega 3 โณ meant specifically eating fish oil . for me , โ supplementing with omega 3 โณ meant adding a scoop of ground flax or chia to my daily diet . surely these are two very different ways of supplementing with omega 3 . in my view it is very important to consistently clarify which form of supplementation is under discussion and which is not , so no one is misled . without these distinctions i think we invite the same sort of confusion that has led to popular myths such as โ all carbs are bad โ . thanks for considering.please , please try to do a video ( or video series ! ) on orthorexia as soon as research is available . it is disheartening to see the overwhelming prevalence of disordered eating in vegan pop culture and is distracting from what truly matters : helping people achieve optimal health and making the world a better place for everyone.there โ s no video but just my two cents on โ orthorexia โ , it โ s a made-up term . eating heathy and wanting to make conscious choices for our families makes logical sense . the reason i don โ t like the word is because it puts those who strive for a healthy diet into an inferior category , where they become labeled perfectionist or idealist . there is more to the story , as one of my dietitian colleagues writes . maybe one day dr. greger can do a video ! to all those below discussing the epa โ s and the dha โ s โ i do not eat fish or take neither supplement . my mind is fine . i do not suffer from depression are have suicidal thoughts.i wonder how incompetent you are , im neurologist toxicologist who study issue about mercury and fish , all mercury scare is scam in japan there is no one screening ( brain ) study showing that currently mercury level is harming so go spread your quackery to children because with their knowledge there is chance tha they belive you in this โ article โ โ pesco-vegetarians in the community , who ate a plant-based diet with up to one serving of fish a day , lived longer than vegan adventists . โ this sentence has circulated on the internet recently . is this true ? if so โฆ how might we account for why eating fish is better than strict vegan ? could it be that the vegan adventists are more junk food vegans as to more whole food plant based ? or maybe the adventists are not taking their vit b12 or omega 3 โ s ? curious as to your thoughts โฆ .. thanks a bunch , charlie ross do alcohol , alzheimer โ s disease , animal fat , animal products , antioxidants , autism , beans , brain disease , brain health , dementia , depression , dha , epa , europe , fat , fish , fruit , greece , harvard , industrial pollutants , japan , meat , mediterranean diet , memory , mental health , mercury , mushrooms , nuts , omega-3 fatty acids , persistent organic pollutants , phytonutrients , red wine , seafood , soy , suicide , vegetables , wine the mercury content in fish may help explain links found between fish intake and mental disorders , depression , and suicide . this reminds me of my video is fish oil just snake oil ? just like we thought omega 3 supplementation could help with mood , we also thought it could help with heart health , but the balance of evidence has decidedly shifted . i still recommend the consumption of pollutant-free sources of preformed long-chain omega 3 โ s for cognitive health โ i have a bunch of videos on their way explaining my rationale.for more on the neurotoxic nature of mercury-contaminated seafood , see : what can we do to help our mood ? see : what about antidepressant drugs . sometimes they can be absolutely life-saving . other times they may actually do more harm than good . see my controversial video do antidepressant drugs really work ?
| arsenic seaweed--forms concentration dietary exposure pubmed ncbi abstract study measured content total inorganic forms arsenic seaweed retail sale consumption provide data dietary exposure estimates support advice consumers total num samples covering varieties seaweed collected retail outlets london internet samples purchased dried product varieties soaking advised prior consumption recommended method preparation individual sample total inorganic arsenic analysed preparation arsenic remaining water soaking measured arsenic detected samples total arsenic concentrations ranging num num mg/kg inorganic arsenic liver cancer found samples hijiki seaweed analysed concentrations range num mg/kg types seaweed found num mg/kg inorganic arsenic limit detection method consumption hijiki seaweed significantly increase dietary exposure inorganic arsenic uk food standards agency fsa issued advice consumers avoid eating
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